Observational studyEuropean heart journal. Cardiovascular Imaging2015
Two-year survival of patients screened for transcatheter aortic valve replacement with potentially malignant incidental findings in initial body computed tomography.
Observational study in European heart journal. Cardiovascular Imaging, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 40 citations in OpenAlex.
- Clinical significance of incidental findings on coronary CT angiography: Insights from a randomized controlled trial.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Trial
- Mortality predictors in cancer patients undergoing transcatheter aortic valve implantation for aortic stenosis: a systematic review and meta-analysis.Cardio-oncology (London, England) · 2026Review
- Prevalence and Clinical Impact of Incidental Extracardiovascular Findings in Pre-TAVI CT Imaging.Journal of clinical medicine · 2025Article
- Article
- Transcatheter aortic valve replacement before to breast cancer management: case report and literature review.European heart journal. Case reports · 2024Article
- Prognosis of patients with active cancer undergoing transcatheter aortic valve implantation: An insight from Japanese multicenter registry.International journal of cardiology. Heart & vasculature · 2022Article
- Incidental findings on computed tomography for preoperative assessment before transcatheter aortic valve implantation in Japanese patients.Heart and vessels · 2021Observational
- Diagnostic Work-Up of the Aortic Patient: An Integrated Approach toward the Best Therapeutic Option.Journal of clinical medicine · 2021Review
- Outcomes of Cancer Patients Undergoing Transcatheter Aortic Valve Replacement.JACC. CardioOncology · 2020Article
- Frequency and impact of incidental findings on computed tomography during work-up for transcatheter aortic valve implantation: single centre experience and review of the literature.The British journal of radiology · 2019Review
- Incidental Non-cardiac Findings in Cardiovascular Imaging.Current treatment options in cardiovascular medicine · 2018Review
- Prognostic impact of myocardial perfusion single photon emission computed tomography in patients with major extracardiac findings by computed tomography for attenuation correction.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018Article
- Extracardiac findings on computed tomography attenuation correction: Is it worth paying extra attention?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018Article
- Incidental findings in multislice computed tomography prior to transcatheter aortic valve implantation: frequency, clinical relevance and outcome.The international journal of cardiovascular imaging · 2018Observational
- Two-year post-discharge costs of care among patients treated with transcatheter or surgical aortic valve replacement in Germany.BMC health services research · 2017Article
- Standard imaging techniques in transcatheter aortic valve replacement.Journal of thoracic disease · 2017Review
- Non-Cardiovascular Computed Tomography Incidental Findings in Patients Who Underwent Transaortic Valve Implantation Procedure.Cardiology research · 2017Article
- The Crucial Role of Cardiac Imaging in Transcatheter Aortic Valve Replacement (TAVR): Pre- and Post-procedural Assessment.Current treatment options in cardiovascular medicine · 2016Review
- Article
- Clinical and economic consequences of non-cardiac incidental findings detected on cardiovascular computed tomography performed prior to transcatheter aortic valve implantation (TAVI).The international journal of cardiovascular imaging · 2015Article
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Authors and funding
13 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsRecently, transcatheter aortic valve replacement (TAVR) has evolved as the standard treatment in patients with inoperable aortic valve stenosis. According to TAVR guidelines, body computed tomography (CT) is recommended for pre-procedural planning. Due to the advanced age of these patients, multiple radiological potentially malignant incidental findings (pmIFs) appear in this cohort. It is unknown how pmIFs influence the decision by the heart team to intervene and the mortality. METHODS AND
resultsWe evaluated in a retrospective single-centre observational study 414 participants screened for TAVR with dual-source CT between October 2010 and December 2012. pmIFs are common and appeared in 18.7% of all patients screened for TAVR. The decision to intervene by TAVR or surgical aortic valve replacement (SAVR) was made by an interdisciplinary heart team and the role of pmIF in decision-making and time to treatment with TAVR or SAVR was analysed, retrospectively. The appearance of a pmIF vs. no pmIF did not significantly influence therapeutic decisions [odds ratio (OR) 1.14; P = 0.835] or time to treatment (91 ± 152 vs. 61 ± 109 days, respectively). Several findings, which are highly suspicious for malignancy, were less likely associated with invasive treatment (OR 0.207; P = 0.046). Patient survival was evaluated for at least 2 years until January 2014. Two-year survival of patients after TAVR or SAVR, treated according to the heart team decision, was ∼75% and independent from the presence of a non-severe (P = 0.923) or severe (P = 0.823) pmIF.
conclusionThe study indicates that frequently occurring radiologic pmIF did not influence 2-year survival after a decision to intervene was made by an interdisciplinary heart team.
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