Evidence map›Paper›PMID 25758837›Full record

Trial reportEuropean journal of clinical nutrition2015

Validation of the omega-3 fatty acid intake measured by a web-based food frequency questionnaire against omega-3 fatty acids in red blood cells in men with prostate cancer.

J Allaire, X Moreel, M-È Labonté, C Léger, A Caron, P Julien, B Lamarche, V Fradet

Open access · bronzeAbstract readClinical Trial, Phase IIValidation Study
PubMed Publisher
In one paragraph

Trial report in European journal of clinical nutrition, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Trial
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  4. Observational
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

J AllaireDepartment of Surgery (Urology), CHU de Québec, L'Hôtel-Dieu de Quebec, Quebec City, Canada.
X MoreelDepartment of Surgery (Urology), CHU de Québec, L'Hôtel-Dieu de Quebec, Quebec City, Canada.
M-È LabontéInstitute of Nutrition and Functional Foods, Laval University, Quebec City, Canada.
C LégerDepartment of Surgery (Urology), CHU de Québec, L'Hôtel-Dieu de Quebec, Quebec City, Canada.
A CaronDepartment of Surgery (Urology), CHU de Québec, L'Hôtel-Dieu de Quebec, Quebec City, Canada.
P JulienCHU de Québec Research Center, Endocrinology and Nephrology Axis, CHU de Québec, Laval University, Quebec City, Canada.
B LamarcheInstitute of Nutrition and Functional Foods, Laval University, Quebec City, Canada.
V FradetDepartment of Surgery (Urology), CHU de Québec, L'Hôtel-Dieu de Quebec, Quebec City, Canada.
Hôtel-Dieu de Québec · CAUniversité Laval · CA

Funding

Canadian Institutes of Health Research
6 · The paper itself

Abstract

BACKGROUND/

objectivesThe objective of this study was to evaluate the ability of a web-based self-administered food frequency questionnaire (web-FFQ) to assess the omega-3 (ω-3) fatty acids (FAs) intake of men affected with prostate cancer (PCa) against a biomarker. SUBJECTS/

methodsThe study presented herein is a sub-study from a phase II clinical trial. Enrolled patients afflicted with PCa were included in the sub-study analysis if the FA profiles from the red blood cell (RBC) membranes and FA intakes at baseline were both determined at the time of the data analysis (n=60). Spearman's correlation coefficients were calculated to estimate the correlations between FA intakes and their proportions in the RBC membranes.

resultsIntakes of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) were highly correlated with their respective proportions in the RBC membranes (both rs=0.593, P<0.0001). Correlation between alpha-linolenic acid (ALA) intake and its proportion in RBC was not significant (rs=0.130, P=0.332). Correlations were observed between fatty fish intake and total ω-3 FAs (rs=0.304, P=0.02), total long-chain ω-3 FAs (rs=0.290, P=0.03) and DHA (rs=0.328, P=0.01) in RBC membranes.

conclusionsThis study has shown that the web-FFQ is an accurate tool to assess total long-chain ω-3 FAs, EPA and DHA but not ALA intake in clinical trials and epidemiological studies carried out in men with PCa.

Indexed as

EatingAgedBiomarkersDiet SurveysErythrocytesFatty Acids, Omega-3Fish ProductsFood AnalysisHumansInternetMaleMiddle AgedProstatic NeoplasmsReproducibility of ResultsStatistics, NonparametricBiomarkersFatty Acids, Omega-3

Identifiers

PMID25758837
OpenAlexW1997303404

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.