ArticleHuman brain mapping2015
Differential relations between juvenile psychopathic traits and resting state network connectivity.
Article in Human brain mapping, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 5 of them syntheses that pooled it.
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Who cites it
27 citing papers in PubMed, 5 syntheses or guidelines pooled it, 73 citations in OpenAlex.
- Using physiological biomarkers in forensic psychiatry: a scoping review.Frontiers in psychiatry · 2025Pooled it
- Clarifying the role of Cortico-Cortical and Amygdalo-Cortical brain dysconnectivity associated with Conduct Problems.NeuroImage. Clinical · 2023Pooled it
- Meta-analytic evidence for a joint neural mechanism underlying response inhibition and state anger.Human brain mapping · 2020Pooled it
- A Systematic Literature Review of Neuroimaging of Psychopathic Traits.Frontiers in psychiatry · 2019Pooled it
- Meta-Analysis of the RDoC Social Processing Domain across Units of Analysis in Children and Adolescents.Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53Pooled it
- Untangling relationships between cognitive development and child and adolescent mental health: Findings from the ABCD Study.Developmental cognitive neuroscience · 2026Review
- Long-term stability of self-reported psychopathic traits in former at-risk adolescents in youth welfare and juvenile justice institutions.Child and adolescent psychiatry and mental health · 2025Article
- Atypical functional connectome is associated with low reflective functioning in incarcerated adolescents.Frontiers in psychiatry · 2024Article
- Antisocial behavior is associated with reduced frontoparietal network efficiency in youth.Social cognitive and affective neuroscience · 2023Article
- Classifying Conduct Disorder Using a Biopsychosocial Model and Machine Learning Method.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2023Article
- Psychopathic traits and altered resting-state functional connectivity in incarcerated adolescent girls.Frontiers in neuroimaging · 2023Article
- Associated functional network connectivity between callous-unemotionality and cognitive and affective empathy.Journal of affective disorders · 2022Article
- Conduct disorder symptomatology is associated with an altered functional connectome in a large national youth sample.Development and psychopathology · 2022Article
- Callous-unemotional traits in adolescents moderate neural network associations with empathy.Psychiatry research. Neuroimaging · 2022Article
- Large-scale functional brain networks of maladaptive childhood aggression identified by connectome-based predictive modeling.Molecular psychiatry · 2022Article
- Callous-unemotional traits and reduced default mode network connectivity within a community sample of children.Development and psychopathology · 2021Article
- Aggression subtypes relate to distinct resting state functional connectivity in children and adolescents with disruptive behavior.European child & adolescent psychiatry · 2021Article
- The longitudinal association between externalizing behavior and frontoamygdalar resting-state functional connectivity in late adolescence and young adulthood.Journal of child psychology and psychiatry, and allied disciplines · 2021Article
- Effect of Methylphenidate on Resting-State Connectivity in Adolescents With a Disruptive Behavior Disorder: A Double-Blind Randomized Placebo-Controlled fMRI Study.Frontiers in psychiatry · 2021Article
- Machine learning approaches for parsing comorbidity/heterogeneity in antisociality and substance use disorders: A primer.Personality neuroscience · 2021Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Traditionally, neurobiological research on psychopathy has focused on categorical differences in adults. However, there is evidence that psychopathy is best described by a set of relatively independent personality dimensions, that is, callous-unemotional, grandiose-manipulative, and impulsive-irresponsible traits, which can be reliably detected in juveniles, allowing investigation of the neural mechanisms leading to psychopathy. Furthermore, complex psychiatric disorders like psychopathy are increasingly being conceptualized as disorders of brain networks. The intrinsic organization of the brain in such networks is reflected by coherent fluctuations in resting state networks (RSNs), but these have not been studied in sufficient detail in relation to juvenile psychopathic traits yet. The current study investigated the distinct associations of juvenile psychopathic traits dimensions with RSN connectivity. Resting-state functional MRI and independent component analysis were used to assess RSN connectivity in a large sample of adolescents (n = 130, mean age 17.8 years) from a childhood arrestee cohort. Associations between scores on each of the three psychopathic traits dimensions and connectivity within and between relevant RSNs were investigated. Callous-unemotional traits were related to aberrant connectivity patterns of the default mode network, which has been implicated in self-referential and moral processes. Impulsive-irresponsible traits were associated with altered connectivity patterns in the frontoparietal cognitive control networks. Grandiose-manipulative traits were not associated with altered connectivity patterns. These findings confirm the association between psychopathic traits and brain network connectivity, and considerably add to emerging evidence supporting neurobiological heterogeneity in the processes leading to psychopathy.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.