Evidence map›Paper›PMID 25757516›Full record

ArticleBMC genomics2015

Human settlement history between Sunda and Sahul: a focus on East Timor (Timor-Leste) and the Pleistocenic mtDNA diversity.

Sibylle M Gomes, Martin Bodner, Luis Souto, Bettina Zimmermann, Gabriela Huber, Christina Strobl, Alexander W Röck, Alessandro Achilli, Anna Olivieri, Antonio Torroni and 2 more

Abstract readHistorical Article
In one paragraph

Article in BMC genomics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

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  9. Mitogenomics of modern Mongolic-speaking populations.Molecular genetics and genomics : MGG · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Sibylle M GomesDepartment of Biology, University of Aveiro, Campus de Santiago, Aveiro, Portugal. sibylle.marcialgomes@ua.pt.
Martin BodnerInstitute of Legal Medicine, Medical University of Innsbruck, Müllerstr. 44, 6020, Innsbruck, Austria. martin.bodner@i-med.ac.at.
Luis SoutoDepartment of Biology, University of Aveiro, Campus de Santiago, Aveiro, Portugal. lsouto@ua.pt.
Bettina ZimmermannInstitute of Legal Medicine, Medical University of Innsbruck, Müllerstr. 44, 6020, Innsbruck, Austria. bettina.zimmermann@i-med.ac.at.
Gabriela HuberInstitute of Legal Medicine, Medical University of Innsbruck, Müllerstr. 44, 6020, Innsbruck, Austria. gabriela.e.huber@i-med.ac.at.
Christina StroblInstitute of Legal Medicine, Medical University of Innsbruck, Müllerstr. 44, 6020, Innsbruck, Austria. christina.strobl@i-med.ac.at.
Alexander W RöckInstitute of Legal Medicine, Medical University of Innsbruck, Müllerstr. 44, 6020, Innsbruck, Austria. a.w.roeck@gmail.com.
Alessandro AchilliDipartimento di Biologia e Biotecnologie "L. Spallanzani", University of Pavia, Pavia, Italy. alessandro.achilli@unipg.it.
Anna OlivieriDipartimento di Biologia e Biotecnologie "L. Spallanzani", University of Pavia, Pavia, Italy. anna.olivieri@unipv.it.
Antonio TorroniDipartimento di Biologia e Biotecnologie "L. Spallanzani", University of Pavia, Pavia, Italy. antonio.torroni@unipv.it.
Francisco Côrte-RealFaculty of Medicine, University of Coimbra, Coimbra, Portugal. fgoncalves@fmed.uc.pt.
Walther ParsonInstitute of Legal Medicine, Medical University of Innsbruck, Müllerstr. 44, 6020, Innsbruck, Austria. walther.parson@i-med.ac.at.

Funding

Austrian Science Fund FWF P 22880
6 · The paper itself

Abstract

backgroundDistinct, partly competing, "waves" have been proposed to explain human migration in(to) today's Island Southeast Asia and Australia based on genetic (and other) evidence. The paucity of high quality and high resolution data has impeded insights so far. In this study, one of the first in a forensic environment, we used the Ion Torrent Personal Genome Machine (PGM) for generating complete mitogenome sequences via stand-alone massively parallel sequencing and describe a standard data validation practice.

resultsIn this first representative investigation on the mitochondrial DNA (mtDNA) variation of East Timor (Timor-Leste) population including >300 individuals, we put special emphasis on the reconstruction of the initial settlement, in particular on the previously poorly resolved haplogroup P1, an indigenous lineage of the Southwest Pacific region. Our results suggest a colonization of southern Sahul (Australia) >37 kya, limited subsequent exchange, and a parallel incubation of initial settlers in northern Sahul (New Guinea) followed by westward migrations <28 kya.

conclusionsThe temporal proximity and possible coincidence of these latter dispersals, which encompassed autochthonous haplogroups, with the postulated "later" events of (South) East Asian origin pinpoints a highly dynamic migratory phase.

Indexed as

PhylogenyAsian PeopleAustraliaChromosomes, Human, YDNA, MitochondrialFemaleGeographyHaplotypesHistory, AncientHuman MigrationHumansMaleMolecular Sequence DataTimor-LesteDNA, Mitochondrial

Identifiers

PMID25757516
PMCPMC4342813

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.