Evidence map›Paper›PMID 25757402›Full record

ArticleScientific reports2015

Multi-scale modeling for the transmission of influenza and the evaluation of interventions toward it.

Dongmin Guo, King C Li, Timothy R Peters, Beverly M Snively, Katherine A Poehling, Xiaobo Zhou

Abstract read
In one paragraph

Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Who Gets the Flu? Individualized Validation of Influenza-like Illness in Urban Spaces.International journal of environmental research and public health · 2023
    Article
  7. Article
  8. Impact of Low Rates of Influenza on Next-Season Influenza Infections.American journal of preventive medicine · 2022
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Influenza surveillance: determining the epidemic threshold for influenza by using the Moving Epidemic Method (MEM), Montenegro, 2010/11 to 2017/18 influenza seasons.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2019
    Article
  17. Review
  18. Mathematical Analysis of Influenza A Dynamics in the Emergence of Drug Resistance.Computational and mathematical methods in medicine · 2018
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dongmin GuoDepartment of Radiology, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
King C LiDepartment of Radiology, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Timothy R PetersDepartment of Pediatrics, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Beverly M SnivelyDepartment of Biostatistical Sciences, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Katherine A Poehling1] Department of Pediatrics, Wake Forest University School of Medicine, Winston-Salem, NC, USA [2] Department of Epidemiology and Prevention, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Xiaobo ZhouDepartment of Radiology, Wake Forest University School of Medicine, Winston-Salem, NC, USA.

Funding

The Movement of Influenza Virus In Human PopulationR01AI079226 · NIAID · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI POEHLING, KATHERINE A · 2009 to 2013
$3.3M
Modelling the Growth of the MIC Niche at the System LevelU01CA166886 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ZHOU, XIAOBO · 2012 to 2016
$2.2M
itNETZ: Integrative and Translational Network-based Cellular Signature AnalyzerU01HL111560 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ZHOU, XIAOBO · 2011 to 2013
$1.1M
NCI NIH HHS U01 CA166886NHLBI NIH HHS U01 HL111560NHLBI NIH HHS U01HL111560-01NIAID NIH HHS R01 AI079226
6 · The paper itself

Abstract

Mathematical modeling of influenza epidemic is important for analyzing the main cause of the epidemic and finding effective interventions towards it. The epidemic is a dynamic process. In this process, daily infections are caused by people's contacts, and the frequency of contacts can be mainly influenced by their cognition to the disease. The cognition is in turn influenced by daily illness attack rate, climate, and other environment factors. Few existing methods considered the dynamic process in their models. Therefore, their prediction results can hardly be explained by the mechanisms of epidemic spreading. In this paper, we developed a heterogeneous graph modeling approach (HGM) to describe the dynamic process of influenza virus transmission by taking advantage of our unique clinical data. We built social network of studied region and embedded an Agent-Based Model (ABM) in the HGM to describe the dynamic change of an epidemic. Our simulations have a good agreement with clinical data. Parameter sensitivity analysis showed that temperature influences the dynamic of epidemic significantly and system behavior analysis showed social network degree is a critical factor determining the size of an epidemic. Finally, multiple scenarios for vaccination and school closure strategies were simulated and their performance was analyzed.

Indexed as

Models, TheoreticalAdolescentAdultAgedAged, 80 and overChildChild, PreschoolComputer SimulationDisease OutbreaksHumansInfantInfant, NewbornInfluenza, HumanMiddle AgedNorth CarolinaPopulation Surveillance

Identifiers

PMID25757402
PMCPMC4355742

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.