ArticleClinical psychological science : a journal of the Association for Psychological Science2015
Obsessive-compulsive disorder is associated with broad impairments in executive function: A meta-analysis.
Article in Clinical psychological science : a journal of the Association for Psychological Science, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04243226 (Develop and Rehabilitation Effects of the Safety Aerobic Exercise Prescription on Cognition, Depression and Quality of Life in Traumatic Brain Injury Patients- Taking the Cerebral Blood Circulation as a Mediator), which is not on this map. Cited by 149 papers, 11 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Develop and Rehabilitation Effects of the Safety Aerobic Exercise Prescription on Cognition, Depression and Quality of Life in Traumatic Brain Injury Patients- Taking the Cerebral Blood Circulation as a Mediator
Who cites it
149 citing papers in PubMed, 11 syntheses or guidelines pooled it.
- Psychotherapy and inhibitory control: Insights from fMRI research.Psychiatry and clinical neurosciences · 2026Pooled it
- Executive functioning in adolescents with internalizing disorders: a systematic review.European child & adolescent psychiatry · 2026Pooled it
- Executive Function in Gambling Disorder: A Meta-analysis on Neuropsychological Evidence.Journal of gambling studies · 2025Pooled it
- Similarities and differences between eating disorders and obsessive-compulsive disorder in childhood and adolescence: a systematic review.Frontiers in psychiatry · 2024Pooled it
- EEG components of inhibitory control ability in internet gaming disorder: A systematic review and meta-analysis of randomized controlled trials.Brain and behavior · 2024Pooled it
- Cognitive outcomes following functional neurosurgery in refractory OCD patients: a systematic review.Neurosurgical review · 2023Pooled it
- Meta-analysis of cognitive functioning in patients with psychotic disorders and obsessive-compulsive symptoms.European archives of psychiatry and clinical neuroscience · 2021Pooled it
- Cognitive Inflexibility in OCD and Related Disorders.Current topics in behavioral neurosciences · 2021Pooled it
- Olfactory Dysfunction in Neurodevelopmental Disorders: A Meta-analytic Review of Autism Spectrum Disorders, Attention Deficit/Hyperactivity Disorder and Obsessive-Compulsive Disorder.Journal of autism and developmental disorders · 2020Pooled it
- Meta-Analysis of Intelligence Quotient (IQ) in Obsessive-Compulsive Disorder.Neuropsychology review · 2018Pooled it
- A systematic review of the neural bases of psychotherapy for anxiety and related disorders.Dialogues in clinical neuroscience · 2015Pooled it
- Childhood cognitive control as a predictor of long-term clinical and functional outcomes in Tourette syndrome.Journal of child psychology and psychiatry, and allied disciplines · 2026Trial
- Investigating the effects of brain stimulation on the neural substrates of inhibition in patients with OCD: A simultaneous tDCS - fMRI study.Translational psychiatry · 2025Trial
- Trial
- Cognitive remediation therapy (CRT) as a treatment enhancer of eating disorders and obsessive compulsive disorders: study protocol for a randomized controlled trial.BMC psychiatry · 2016Trial
- Distinct structural abnormalities in obsessive-compulsive and alcohol use disorders.European archives of psychiatry and clinical neuroscience · 2026Article
- Electrophysiological Correlates of Cognitive Dysfunction in Obsessive-Compulsive Disorder (OCD): A Systematic and Mechanistic Review of EEG, ERP, and QEEG Evidence.Journal of clinical medicine · 2026Review
- Antisaccade Performance in Adolescent Obsessive-Compulsive Disorder: Evidence from a Familial-Risk Design.Journal of eye movement research · 2026Article
- Parent- and child-reported executive functioning and response to psychotherapy in pediatric obsessive-compulsive disorder: Results from the TECTO study.European child & adolescent psychiatry · 2026Article
- App-based mindfulness meditation training enhances cognitive flexibility and modulates ACC and medial frontal gyrus activation during task switching in adolescent OCD.Neuroimage. Reports · 2026Article
89 more citing papers are in PubMed but not listed here.
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Authors and funding
4 authors.
Funding
Abstract
Obsessive-compulsive disorder (OCD) is a serious and often chronically disabling condition. The current dominant model of OCD focuses on abnormalities in prefrontal-striatal circuits that support executive function (EF). While there is growing evidence for EF impairments associated with OCD, results have been inconsistent, making the nature and magnitude of these impairments controversial. The current meta-analysis uses random-effects models to synthesize 110 previous studies that compared participants with OCD to healthy control participants on at least one neuropsychological measure of EF. The results indicate that individuals with OCD are impaired on tasks measuring most aspects of EF, consistent with broad impairment in EF. EF deficits were not explained by general motor slowness or depression. Effect sizes were largely stable across variation in demographic and clinical characteristics of samples, although medication use, age, and gender moderated some effects.
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