Evidence map›Paper›PMID 25755893›Full record

ArticleNew microbes and new infections2015

Cryptococcus neoformans meningitis with negative cryptococcal antigen: Evaluation of a new immunochromatographic detection assay.

O Opota, B Desgraz, A Kenfak, K Jaton, M Cavassini, G Greub, G Prod'hom, S Giulieri

Abstract read
In one paragraph

Article in New microbes and new infections, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Performance of the Colloidal Gold Immunochromatography of Cryptococcal Antigen on Bronchoalveolar Lavage Fluid for the Diagnosis of Pulmonary Cryptococcosis.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2022
    Article
  2. Article
  3. Article
  4. Review
  5. CSF in acute and chronic infectious diseases.Handbook of clinical neurology · 2017
    Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

O OpotaInstitute of Microbiology, Switzerland.
B DesgrazInfectious Diseases Service, University of Lausanne and University Hospital Center, Lausanne, Switzerland.
A KenfakInfectious Diseases Service, University of Lausanne and University Hospital Center, Lausanne, Switzerland.
K JatonInstitute of Microbiology, Switzerland.
M CavassiniInfectious Diseases Service, University of Lausanne and University Hospital Center, Lausanne, Switzerland.
G GreubInstitute of Microbiology, Switzerland ; Infectious Diseases Service, University of Lausanne and University Hospital Center, Lausanne, Switzerland.
G Prod'homInstitute of Microbiology, Switzerland.
S GiulieriInfectious Diseases Service, University of Lausanne and University Hospital Center, Lausanne, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Detection of cryptococcal antigen in serum or cerebrospinal fluid allows cryptococcal meningitis diagnosis within few hours with >90% sensitivity. In an HIV-positive patient with Cryptococcus neoformans meningitis, initial antigen detection by immunoagglutination was negative. We thus evaluated a new immunochromatographic detection assay that exhibited a higher sensitivity.

Indexed as

Antigen testCryptococcus neoformansHIVimmunochromatographymeningitis

Identifiers

PMID25755893
PMCPMC4337943

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.