ArticleInternational journal of clinical and experimental pathology2015
Combined detections of interleukin-33 and adenosine deaminase for diagnosis of tuberculous pleural effusion.
Article in International journal of clinical and experimental pathology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Diagnostic value of interleukins for tuberculous pleural effusion: a systematic review and meta-analysis.BMC pulmonary medicine · 2017Pooled it
- Occurrence of drug resistance, associated risk factors, and expression of cytokine IL-33 in human TB patients.Annals of medicine and surgery (2012) · 2026Article
- The large language model diagnoses tuberculous pleural effusion in pleural effusion patients through clinical feature landscapes.Respiratory research · 2025Article
- Diagnostic value of combined pleural interleukin-33, adenosine deaminase and peripheral blood tuberculosis T cell spot detection TB for tuberculous pleurisy.BMC infectious diseases · 2021Article
- Potential diagnostic value of pleural fluid cytokines levels for tuberculous pleural effusion.Scientific reports · 2021Article
- Pleural Effusion IL-33/sST2 Levels and Effects of Low and High IL-33/sST2 Levels on Human Mesothelial Cell Adhesion and Migration.Inflammation · 2019Article
- IgA and IgG antibody detection of mycobacterial antigens in pleural fluid and serum from pleural tuberculous patients.BMC immunology · 2019Article
- Identifying tuberculous pleural effusion using artificial intelligence machine learning algorithms.Respiratory research · 2019Article
- Diagnostic role of interleukin -33 in the differentiation of pleural effusions especially tuberculous and malignant effusions.BMC pulmonary medicine · 2019Article
- Pleural IFN-γ release assay combined with biomarkers distinguished effectively tuberculosis from malignant pleural effusion.BMC infectious diseases · 2019Article
- Diagnostic value of T-Spot TB combined with INF-γ and IL-27 in tuberculous pleurisy.Experimental and therapeutic medicine · 2018Article
- Combined evaluation of adenosine deaminase level and histopathological findings from pleural biopsy with Cope's needle for the diagnosis of tuberculous pleurisy.International journal of clinical and experimental pathology · 2015Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate the diagnostic accuracy of the combination of interleukin-33 (IL-33) and adenosine deaminase (ADA) for differentiating TPE from pleural effusions with the other etiologies.
methodsPleural effusion samples were collected from 32 TPE patients and 55 non-TPE patients. Pleural levels of IL-33 and ADA were measured by ELISA. The corresponding biochemical indexes were also simultaneously determined.
resultsThe pleural levels of IL-33 and ADA in the TPE group were significantly higher than those in the non-TPE group. With a cut-off value of 68.3 pg/ml, the sensitivity and specificity for IL-33 were 83.9% and 70.9%, respectively. While for ADA, the sensitivity and specificity were 87.5% and 87.3%, respectively at a cut-off value of 10.25 U/L. Combined use of IL-33 and ADA measurements further increased the sensitivity or specificity.
conclusionOur study suggests that the applications of new biomarker IL-33, along with ADA, may serve as efficient diagnosis strategies in the management of pleural TB. Further studies at a large scale should be performed to validate our findings.
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