ArticleComputational and mathematical methods in medicine2015
Tactics and strategies for managing Ebola outbreaks and the salience of immunization.
Article in Computational and mathematical methods in medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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12 citing papers in PubMed.
- Evaluating the impact of trade-offs in diagnostic test accuracy, time-to-isolation, and accessibility on outbreak response for the Ebola virus: a mathematical modeling study.BMC infectious diseases · 2025Article
- Simulation applications to support teaching and research in epidemiological dynamics.BMC medical education · 2022Article
- A runtime alterable epidemic model with genetic drift, waning immunity and vaccinations.Journal of the Royal Society, Interface · 2021Article
- Enhanced surveillance and response approaches for pilgrims and local Saudi populations against emerging Nipah, Zika and Ebola viral diseases outbreaks threats.Journal of infection and public health · 2020Review
- Adequacy of SEIR models when epidemics have spatial structure: Ebola in Sierra Leone.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2019Article
- Article
- Discrete stochastic analogs of Erlang epidemic models.Journal of biological dynamics · 2018Article
- [Outbreak of Ébola in Lunsar. Effectiveness of a socio-sanitary intervention].Revista espanola de salud publica · 2018Article
- An Agent-Based Model of School Closing in Under-Vacccinated Communities During Measles Outbreaks.Agent-Directed Simulation Symposium (ADS). Agent-directed Simulation Symposium · 2016Article
- Modeling household and community transmission of Ebola virus disease: Epidemic growth, spatial dynamics and insights for epidemic control.Virulence · 2016Article
- Panmictic and Clonal Evolution on a Single Patchy Resource Produces Polymorphic Foraging Guilds.PloS one · 2015Article
- Article
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Authors and funding
10 authors.
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Abstract
We present a stochastic transmission chain simulation model for Ebola viral disease (EVD) in West Africa, with the salutary result that the virus may be more controllable than previously suspected. The ongoing tactics to detect cases as rapidly as possible and isolate individuals as safely as practicable is essential to saving lives in the current outbreaks in Guinea, Liberia, and Sierra Leone. Equally important are educational campaigns that reduce contact rates between susceptible and infectious individuals in the community once an outbreak occurs. However, due to the relatively low R 0 of Ebola (around 1.5 to 2.5 next generation cases are produced per current generation case in naïve populations), rapid isolation of infectious individuals proves to be highly efficacious in containing outbreaks in new areas, while vaccination programs, even with low efficacy vaccines, can be decisive in curbing future outbreaks in areas where the Ebola virus is maintained in reservoir populations.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.