ReviewFrontiers in psychiatry2015
Chronic subordinate colony housing paradigm: a mouse model to characterize the consequences of insufficient glucocorticoid signaling.
Review in Frontiers in psychiatry, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
35 citing papers in PubMed, 65 citations in OpenAlex.
- Microbial Legacy: Mycobacterium vaccae ATCC 15483Molecular psychiatry · 2026Article
- Role of Antioxidant Systems and Heat Shock Response in Aquatic Animals Under Multistress Conditions.Antioxidants (Basel, Switzerland) · 2026Review
- Short- and Long-Term Effects of Social Isolation on Adult Murine Bone are Sex-Dependent.bioRxiv : the preprint server for biology · 2026Article
- <italic>Mycobacterium vaccae</italic> NCTC 11659 Attenuates Early Life Adversity-Induced Hippocampal Neuroinflammation in Mice.Neuroimmunomodulation · 2026Article
- Behavioral coping with chronic defeat stress in mice: A systematic review of current protocols.Neurobiology of stress · 2024Review
- Chronic sensory contact with subordinated conspecifics promotes splenic glucocorticoid resistance in experimentally wounded C57BL/6N male mice.Scientific reports · 2024Article
- Mitochondrial morphology in the mouse adrenal cortex: Influence of chronic psychosocial stress.Psychoneuroendocrinology · 2024Article
- Effects of repeated intragastric administrations with heat-inactivatedFrontiers in neuroscience · 2024Article
- Fracture healing research: Recent insights.Bone reports · 2023Review
- Long-term effects of chronic stress models in adult mice.Journal of neural transmission (Vienna, Austria : 1996) · 2023Review
- SubcutaneousNeurobiology of stress · 2023Article
- Neutrophil-derived catecholamines mediate negative stress effects on bone.Nature communications · 2023Article
- Intact GR dimerization is critical for restraining plasma ACTH levels during chronic psychosocial stress.Neurobiology of stress · 2023Article
- Effect of Caging onMicroorganisms · 2022Article
- Article
- Consequences of pandemic-associated social restrictions: Role of social support and the oxytocin system.Psychoneuroendocrinology · 2022Review
- Understanding stress: Insights from rodent models.Current research in neurobiology · 2021Review
- Changes in Functional Glucocorticoid Sensitivity of Isolated Splenocytes Induced by Chronic Psychosocial Stress - A Time Course Study.Frontiers in immunology · 2021Article
- Effects of Immunization With the Soil-Derived BacteriumFrontiers in physiology · 2020Article
- Chronic psychosocial stress compromises the immune response and endochondral ossification during bone fracture healing via β-AR signaling.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chronic, in particular chronic psychosocial, stress is a burden of modern societies and known to be a risk factor for numerous somatic and affective disorders (in detail referenced below). However, based on the limited existence of appropriate, and clinically relevant, animal models for studying the effects of chronic stress, the detailed behavioral, physiological, neuronal, and immunological mechanisms linking stress and such disorders are insufficiently understood. To date, most chronic stress studies in animals employ intermittent exposure to the same (homotypic) or to different (heterotypic) stressors of varying duration and intensity. Such models are only of limited value, since they do not adequately reflect the chronic and continuous situation that humans typically experience. Furthermore, application of different physical or psychological stimuli renders comparisons to the mainly psychosocial stressors faced by humans, as well as between the different stress studies almost impossible. In contrast, rodent models of chronic psychosocial stress represent situations more akin to those faced by humans and consequently seem to hold more clinical relevance. Our laboratory has developed a model in which mice are exposed to social stress for 19 continuous days, namely the chronic subordinate colony housing (CSC) paradigm, to help bridge this gap. The main aim of the current review article is to provide a detailed summary of the behavioral, physiological, neuronal, and immunological consequences of the CSC paradigm, and wherever possible relate the findings to other stress models and to the human situation.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.