Evidence map›Paper›PMID 25755601›Full record

ReviewJournal of clinical and experimental hepatology2014

Role of local ablative therapy for hepatocellular carcinoma.

Ragesh B Thandassery, Usha Goenka, Mahesh K Goenka

Abstract readReview
In one paragraph

Review in Journal of clinical and experimental hepatology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ragesh B ThandasseryInstitute of Gastroscience, Apollo Gleneagles Hospital, Kolkata, West Bengal, India.
Usha GoenkaInstitute of Gastroscience, Apollo Gleneagles Hospital, Kolkata, West Bengal, India.
Mahesh K GoenkaInstitute of Gastroscience, Apollo Gleneagles Hospital, Kolkata, West Bengal, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Percutaneous local ablation (PLA) techniques are currently considered as the best treatment option for patients with early-stage hepatocellular carcinoma (HCC) who are not candidates for surgical resection. They are safe, minimally invasive, efficacious and cost-effective. Radiofrequency ablation (RFA) is considered as the first line treatment in some centers, though most of the guidelines recommend it for small HCCs, where surgical resection is not feasible. In developing countries percutaneous ethanol injection (PEI) and percutaneous acetic acid injection (PAI) may be used instead of RFA. For large HCCs, advances in electrode designs and newer techniques of ablation, including microwave ablation, are increasingly been used. Combination treatment modalities have shown promising results as compared to single modality for large tumors. The selection of the most appropriate modality depends on the size, number of lesions, the liver function status, patient's financial resources, availability of a particular technique and the expertise available.

Indexed as

AFP, alpha feto proteinCT, computed tomographyHCC, hepatocellular carcinomahepatocellular carcinoma (HCC)HR, hepatic resectionPEI, percutaneous ethanol injectionpercutaneous liver ablation (PLA)PLA, percutaneous local ablationradiofrequency ablation (RFA)RFA, radiofrequency ablationUSG, ultrasonography

Identifiers

PMID25755601
PMCPMC4284241

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.