Evidence map›Paper›PMID 25755581›Full record

ReviewJournal of clinical and experimental hepatology2014

Infections after orthotopic liver transplantation.

Mark Pedersen, Anil Seetharam

Open access · bronzeAbstract readReview
In one paragraph

Review in Journal of clinical and experimental hepatology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Role of Lymphopenia in Early prediction of Infection Following Orthotopic Liver Transplantation in Cirrhotic Patients.Transplant international : official journal of the European Society for Organ Transplantation · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Observational
  14. Article
  15. Observational
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Mark PedersenUniversity of Arizona College of Medicine Phoenix, Banner Transplant and Advanced Liver Disease Center, Phoenix, AZ 85006, USA.
Anil SeetharamUniversity of Arizona College of Medicine Phoenix, Banner Transplant and Advanced Liver Disease Center, Phoenix, AZ 85006, USA.
Phoenix (United States) · USUniversity of Arizona · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Opportunistic infections are a leading cause of morbidity and mortality after orthotopic liver transplantation. Systemic immunosuppression renders the liver recipient susceptible to de novo infection with bacteria, viruses and fungi post-transplantation as well to reactivation of pre-existing, latent disease. Pathogens are also transmissible via the donor organ. The time from transplantation and degree of immunosuppression may guide the differential diagnosis of potential infectious agents. However, typical systemic signs and symptoms of infection are often absent or blunted after transplant and a high index of suspicion is needed. Invasive procedures are often required to procure tissue for culture and guide antimicrobial therapy. Antimicrobial prophylaxis reduces the incidence of opportunistic infections and is routinely employed in the care of patients after liver transplant. In this review, we survey common bacterial, fungal, and viral infections after orthotopic liver transplantation and highlight recent developments in their diagnosis and management.

Indexed as

BAL, bronchoalveolar lavageCMV, cytomegaloviruscytomegalovirusdonor transmissionEBV, epstein–Barr virusELISA, enzym linked immunosorbent assayFCN2, ficolin-2GM, galactomannanHAT, hepatic artery thrombosisHBIG, hepatitis B immune globulinHBV, hepatitis B virusHCV, hepatitis C virusHHV, human herpesvirusinfectionLDLT, live donor liver transplantationliver transplantationMASP2, MBL-associated serine proteaseMBL, mannan-binding lectinMDR, multi-drug resistantMELD, model for end-stage liver diseaseNAS, non-anastomotic strictureOLT, orthotopic liver transplantationPPD, purified protein derivativeprophylaxisPTLD, post-transplant lymphoproliferative disorderSNP, single nucleotide polymorphismTLR, toll-like receptorU, unit

Identifiers

PMID25755581
PMCPMC4298628
OpenAlexW1994239855

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.