Evidence map›Paper›PMID 25755551›Full record

ReviewJournal of clinical and experimental hepatology2014

Pregnancy-related liver disorders.

Ashish Goel, Kapil D Jamwal, Anup Ramachandran, Kunissery A Balasubramanian, Chundamannil E Eapen

Open access · bronzeAbstract readReview
In one paragraph

Review in Journal of clinical and experimental hepatology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 2 pooled it
6.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 2 syntheses or guidelines pooled it, 86 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Sexual dimorphism in the liver.Nature reviews. Gastroenterology & hepatology · 2026
    Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Analysis of a case of severe pancreatitis complicated with preeclampsia.The Journal of international medical research · 2025
    Article
  9. Article
  10. Article
  11. Review
  12. Acute liver failure in pregnancy.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2024
    Review
  13. Review
  14. Article
  15. Liver Diseases in the Parturient.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2021
    Article
  16. State of the Art in Hepatic Dysfunction in Pregnancy.Healthcare (Basel, Switzerland) · 2021
    Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ashish GoelDepartment of Hepatology, Division of Gastrointestinal Sciences, Christian Medical College, Vellore 632004, Tamil Nadu, India.
Kapil D JamwalDepartment of Hepatology, Division of Gastrointestinal Sciences, Christian Medical College, Vellore 632004, Tamil Nadu, India.
Anup RamachandranDepartment of Wellcome Research Unit, Division of Gastrointestinal Sciences, Christian Medical College, Vellore 632004, Tamil Nadu, India.
Kunissery A BalasubramanianDepartment of Wellcome Research Unit, Division of Gastrointestinal Sciences, Christian Medical College, Vellore 632004, Tamil Nadu, India.
Chundamannil E EapenDepartment of Hepatology, Division of Gastrointestinal Sciences, Christian Medical College, Vellore 632004, Tamil Nadu, India.
Christian Medical College & Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pregnancy-related liver disorders accounted for 8% of all maternal deaths at our center from 1999 to 2011. Of the three pregnancy-related liver disorders (acute fatty liver of pregnancy (AFLP), HELLP (Hemolysis, elevated liver enzymes, low platelets) syndrome and pre-eclamptic liver dysfunction, which can lead to adverse maternal and fetal outcome, AFLP is most typically under - diagnosed. Risk of maternal death can be minimised by timely recognition and early/aggressive multi-specialty management of these conditions. Urgent termination of pregnancy remains the cornerstone of therapy for some of these life threatening disorders, but recent advancements in our understanding help us in better overall management of these patients. This review focuses on various aspects of pregnancy-related liver disorders.

Indexed as

acute fatty liver of pregnancyAFLP, acute fatty liver of pregnancyCS, CaesareanFAO, fatty acid oxidationHbsAg, hepatitis B surface antigenHELLP, hemolysis elevated liver enzymes and low plateletsHELLP syndromeHG, hyperemesis gravidarumICP, intrahepatic cholestasis of pregnancyLCHAD, long chain hydroxyacyl coA dehydrogenaseLDH, lactate dehydrogenaseLFT, liver function testsmaternal mortalityMP, malarial parasiteMTP, mitochondrial tri-functional proteinPFIC, progressive familial intra-hepatic cholestasispre-eclampsiaPRLD, pregnancy-related liver disordersPT, prothrombin timeUDCA, ursodeoxycholic acid

Identifiers

PMID25755551
PMCPMC4116710
OpenAlexW2091581462

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.