Evidence map›Paper›PMID 25755384›Full record

ArticleJournal of clinical and experimental hepatology2011

Occult hepatitis C virus infection and its relevance in clinical practice.

Tram Nq Pham, Tomasz I Michalak

Abstract read
In one paragraph

Article in Journal of clinical and experimental hepatology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Epidemiology of hepatitis C virus in Iran.World journal of gastroenterology · 2015
    Review
  10. A New Twist to a Chronic HCV Infection: Occult Hepatitis C.Gastroenterology research and practice · 2015
    Review
  11. Hepatobiliary quiz-12 (2014).Journal of clinical and experimental hepatology · 2014
    Article
  12. Answers to multiple choice questions.Journal of clinical and experimental hepatology · 2012
    Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Tram Nq PhamMolecular Virology and Hepatology Research Group, Division of Biomedical Sciences, Faculty of Medicine, Health Sciences Center, Memorial University, St. John's, NL, Canada A1B 3V6.
Tomasz I MichalakMolecular Virology and Hepatology Research Group, Division of Biomedical Sciences, Faculty of Medicine, Health Sciences Center, Memorial University, St. John's, NL, Canada A1B 3V6.
Memorial University of Newfoundland · CASt. John's University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatitis C virus (HCV) can persist in the liver, lymphoid (immune) cells, and serum of individuals long after an apparently complete therapy-induced or a spontaneous resolution of hepatitis C. This essential asymptomatic infection, called secondary occult HCV infection (OCI), usually occurs in anti-HCV antibody reactive individuals with normal liver function tests. This infection has been identified when the nucleic acid amplification assays of enhanced sensitivity were applied for the detection of HCV genome and its replication. In addition to the secondary OCI, a form of low-level HCV-RNA-positive infection of unknown etiology coinciding with moderately elevated serum liver enzymes and progressing in the absence of anti-HCV detectable by standard clinical assays has been reported. Because of its undefined origin, it can be termed cryptogenic OCI. In this review, the general characteristics of OCI, the ways of its detection and associated controversies, and the potential clinical implications of its existence will be concisely outlined.

Indexed as

CHC, chronic hepatitis CClinical practiceHBV, hepatitis B virusHCC, hepatocellular carcinomaHCV, hepatitis C virushepatitis Cidentification of OCIIFN, interferonIU, international unitNAH, nucleic acid hybridizationoccult HCV infectionOCI, occult HCV infectionPBMC, peripheral blood mononuclear cellsPCR, polymerase chain reactionRBV, ribavirinRNA, ribonucleic acidSVR, sustained virological response

Identifiers

PMID25755384
PMCPMC3940301
OpenAlexW2066716452

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.