Evidence map›Paper›PMID 25755308›Full record

ArticleJournal of clinical and experimental hepatology2011

Latent Mycobacterium tuberculosis Infection in Liver Transplant Recipients-Controversies in Current Diagnosis and Management.

Srinivas Rajagopala, A Olithselvan, Joy Varghese, Naresh Shanmugam, Mohamed Rela

Abstract read
In one paragraph

Article in Journal of clinical and experimental hepatology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Fluoroquinolones for the treatment of latentWorld journal of gastroenterology · 2019
    Review
  4. A guide to the management of tuberculosis in patients with chronic liver disease.Journal of clinical and experimental hepatology · 2012
    Review
  5. Hepatobiliary quiz-3 (2012).Journal of clinical and experimental hepatology · 2012
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Srinivas RajagopalaInstitute of Liver Disease and Transplantation, Global Hospitals, Chennai, India.
A OlithselvanInstitute of Liver Disease and Transplantation, Global Hospitals, Chennai, India.
Joy VargheseInstitute of Liver Disease and Transplantation, Global Hospitals, Chennai, India.
Naresh ShanmugamInstitute of Liver Disease and Transplantation, Global Hospitals, Chennai, India.
Mohamed RelaInstitute of Liver Disease and Transplantation, Global Hospitals, Chennai, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liver transplantation for end-stage liver disease is increasingly being undertaken in India.(1) Routine tuberculin skin testing (TST) for latent Mycobacterium tuberculosis infection (LTBI) and isoniazid prophylaxis in TST-positive liver-transplant recipients (LTRs) is recommended(2,3) but seldom implemented worldwide.(4-7) The role of TST-testing and isoniazid prophylaxis in LTRs remains further undefined in high prevalence areas, including India. We describe the burden of LTBI in LTRs; the epidemiological aspects of M. tuberculosis infection in high prevalence areas; identifiable risk factors for M. tuberculosis infection; the limitations of current diagnostic techniques for LTBI in LTRs and the efficacy and toxicity of isoniazid prophylaxis in TST-positive LTRs and suggest directions for future investigations in this area.

Indexed as

ATT, anti-tuberculosis medicationsHCWs, healthcare workersIGRA, IFN-γ release assaysIsoniazid prophylaxislatent tuberculosis infectionliver transplantationLTBI, latent Mycobacterium tuberculosis infectionLTRs, liver-transplant recipientsLT-TB, liver transplantation tuberculosissolid organ transplantationSOT, solid-organ transplantTST, tuberculin skin testingtuberculosis

Identifiers

PMID25755308
PMCPMC3940303

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.