ReviewJournal of dental research2015
Glycosyltransferase-mediated Sweet Modification in Oral Streptococci.
Review in Journal of dental research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 54 citations in OpenAlex.
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- Berberine Attenuates Chromobacterium violaceum's Virulence by Targeting Efflux and Denitrification Machinery.Chemistry & biodiversity · 2026Article
- Ability of the Chinese herbal residue to alleviate short-distance transportation stress in sheep through the remodeling of the rumen microbiome-metabolism axis.Journal of animal science and biotechnology · 2026Article
- Berberine, the major bioactive compound frombioRxiv : the preprint server for biology · 2025Article
- Study on the Plateau Adaptive Synergistic Mechanism of Rumen Microbiome-Metabolome-Resistome in Tibetan Sheep.Microorganisms · 2025Article
- Antimicrobial, remineralization, and infiltration: advanced strategies for interrupting dental caries.Medical review (2021) · 2025Review
- Comparative analysis of biofilm structures in Salmonella Typhimurium DMC4 strain and its dam and seqA gene mutants using Fourier transform infrared spectroscopy (FT-IR) and Raman spectroscopy methods.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025Article
- Differences in Gut Microbial Composition and Characteristics Among Three Populations of the Bamboo Pitviper (Ecology and evolution · 2024Article
- Terahertz Imaging Detects Oral Cariogenic Microbial Domains Characteristics.Journal of dental research · 2024Article
- Environmental Driving of Adaptation Mechanism on Rumen Microorganisms of Sheep Based on Metagenomics and Metabolomics Data Analysis.International journal of molecular sciences · 2024Article
- In Silico Molecular Docking of Phytochemicals of Murraya koenigii Against Streptococcus mutans.Cureus · 2024Article
- Structural Determination of Glucosyltransferase C by Cryo-Electron Microscopy.Methods in molecular biology (Clifton, N.J.) · 2024Article
- The Effect of Mushroom Dietary Fiber on the Gut Microbiota and Related Health Benefits: A Review.Journal of fungi (Basel, Switzerland) · 2023Review
- Comparative Functional Genome Analysis Reveals the Habitat Adaptation and Biocontrol Characteristics of Plant Growth-Promoting Bacteria in NCBI Databases.Microbiology spectrum · 2023Article
- Article
- The Comparative Analysis of Genomic Diversity and Genes Involved in Carbohydrate Metabolism of Eighty-EightNutrients · 2022Article
- The vicK gene of Streptococcus mutans mediates its cariogenicity via exopolysaccharides metabolism.International journal of oral science · 2021Article
- Molecular mechanisms of inhibiting glucosyltransferases for biofilm formation in Streptococcus mutans.International journal of oral science · 2021Review
- The Current Strategies in Controlling Oral Diseases by Herbal and Chemical Materials.Evidence-based complementary and alternative medicine : eCAM · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Bacterial glycosyltransferases play important roles in bacterial fitness and virulence. Oral streptococci have evolved diverse strategies to survive and thrive in the carbohydrate-rich oral cavity. In this review, we discuss 2 important biological processes mediated by 2 distinct groups of glycosyltransferases in oral streptococci that are important for bacterial colonization and virulence. The first process is the glycosylation of highly conserved serine-rich repeat adhesins by a series of glycosyltransferases. Using Streptococcus parasanguinis as a model, we highlight new features of several glycosyltransferases that sequentially modify the serine-rich glycoprotein Fap1. Distinct features of a novel glycosyltransferase fold from a domain of unknown function 1792 are contrasted with common properties of canonical glycosyltransferases. The second biological process we cover is involved in building sticky glucan matrix to establish cariogenic biofilms by an important opportunistic pathogen Streptococcus mutans through the action of a family of 3 glucosyltransferases. We focus on discussing the structural feature of this family as a glycoside hydrolase family of enzymes. While the 2 processes are distinct, they all produce carbohydrate-coated biomolecules, which enable bacteria to stick better in the complex oral microbiome. Understanding the making of the sweet modification presents a unique opportunity to develop novel antiadhesion and antibiofilm strategies to fight infections by oral streptococci and beyond.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.