ArticlePlant physiology2015
LACCASE5 is required for lignification of the Brachypodium distachyon Culm.
Article in Plant physiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
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Who cites it
43 citing papers in PubMed, 92 citations in OpenAlex.
- Genome-wide characterization of the LAC gene family in five fern species reveals evolutionary diversification and putative roles in lignin biosynthesis in Alsophila spinulosa.BMC plant biology · 2026Article
- Quantitative resistance toFrontiers in plant science · 2026Article
- Comparative transcriptomics in ferns reveals key innovations and divergent evolution of the secondary cell walls.Nature plants · 2025Article
- Heterologous expression ofPhysiology and molecular biology of plants : an international journal of functional plant biology · 2024Article
- Article
- The Laccase Family GenePlants (Basel, Switzerland) · 2024Article
- Review
- Grass lignin: biosynthesis, biological roles, and industrial applications.Frontiers in plant science · 2024Review
- Comprehensive analysis of the laccase gene family in tea plant highlights its roles in development and stress responses.BMC plant biology · 2023Article
- Study on Characteristics and Lignification Mechanism of Postharvest Banana Fruit during Chilling Injury.Foods (Basel, Switzerland) · 2023Article
- Genome-wide analysis of the laccase (LAC) gene family inFrontiers in plant science · 2023Article
- The Citrus Laccase GeneInternational journal of molecular sciences · 2022Article
- Plant Cell Wall Proteomes: The Core of Conserved Protein Families and the Case of Non-Canonical Proteins.International journal of molecular sciences · 2022Review
- Construction of a high-density bin-map and identification of fruit quality-related quantitative trait loci and functional genes in pear.Horticulture research · 2022Article
- The MicroRNA397a-LACCASE17 module regulates lignin biosynthesis inFrontiers in plant science · 2022Article
- Spatio-Temporal Modification of Lignin Biosynthesis in Plants: A Promising Strategy for Lignocellulose Improvement and Lignin Valorization.Frontiers in bioengineering and biotechnology · 2022Review
- Article
- Investigation of cell wall proteins of C. sinensis leaves by combining cell wall proteomics and N-glycoproteomics.BMC plant biology · 2021Article
- Localised laccase activity modulates distribution of lignin polymers in gymnosperm compression wood.The New phytologist · 2021Article
- Phenoloxidases in Plants-How Structural Diversity Enables Functional Specificity.Frontiers in plant science · 2021Review
Corrections and comments
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Authors and funding
14 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The oxidation of monolignols is a required step for lignin polymerization and deposition in cell walls. In dicots, both peroxidases and laccases are known to participate in this process. Here, we provide evidence that laccases are also involved in the lignification of Brachypodium distachyon, a model plant for temperate grasses. Transcript quantification data as well as in situ and immunolocalization experiments demonstrated that at least two laccases (LACCASE5 and LACCASE6) are present in lignifying tissues. A mutant with a misspliced LACCASE5 messenger RNA was identified in a targeting-induced local lesion in genome mutant collection. This mutant shows 10% decreased Klason lignin content and modification of the syringyl-to-guaiacyl units ratio. The amount of ferulic acid units ester linked to the mutant cell walls is increased by 40% when compared with control plants, while the amount of ferulic acid units ether linked to lignins is decreased. In addition, the mutant shows a higher saccharification efficiency. These results provide clear evidence that laccases are required for B. distachyon lignification and are promising targets to alleviate the recalcitrance of grass lignocelluloses.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.