Evidence map›Paper›PMID 25755093›Full record

Trial reportObesity (Silver Spring, Md.)2015

Usual breakfast eating habits affect response to breakfast skipping in overweight women.

Elizabeth A Thomas, Janine Higgins, Daniel H Bessesen, Bryan McNair, Marc-Andre Cornier

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Obesity (Silver Spring, Md.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. Impact of breakfast consumption timingThe British journal of nutrition · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Elizabeth A ThomasDivision of Endocrinology, Metabolism and Diabetes, Department of Medicine, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, Colorado, USA; Anschutz Health and Wellness Center, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
Janine Higgins
Daniel H Bessesen
Bryan McNair
Marc-Andre Cornier

Funding

Colorado Clinical and Translational Sciences InstituteUL1TR001082 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2013 to 2017
$48.0M
PILOT STUDY--SUBSTRATE METABOLISM IN EXTREMELY LOW BIRTH WEIGHT INFANTSP30DK048520 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI Edward L Melanson · 1995 to 2026
$32.6M
TRAINING PROGRAM IN DIABETES, ENDOCRINOLOGY &METABOLISMT32DK007446 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI BESSESEN, DANIEL HOLLAND · 1986 to 2017
$5.6M
NCATS NIH HHS UL1 TR001082NIDDK NIH HHS 5P30DK048520NIDDK NIH HHS 5 T32 DK007446-30NIDDK NIH HHS P30 DK048520NIDDK NIH HHS T32 DK007446
6 · The paper itself

Abstract

objectiveThis randomized, cross-over trial was designed to investigate the metabolic and appetitive responses to skipping breakfast in overweight women who were habitual breakfast Eaters or Skippers.

methodsNine Eaters and nine Skippers were studied on two separate days during which subjects ate breakfast (B) or had no breakfast (NB), followed by a standard lunch meal 4 h later. Blood sampling for hormones and metabolites was performed after lunch, and appetite was rated throughout the day.

resultsInteractions between day and habitual breakfast pattern were seen for area under the curve (AUC) for insulin and free fatty acids (FFA). Both insulin (P = 0.020) and FFA (P = 0.023) AUC were higher on the NB day for Eaters but similar on both days for Skippers. Eaters had higher pre lunch hunger AUC on the NB day (P = 0.015) as well as lower pre lunch satiety AUC under both conditions (P = 0.019).

conclusionsOverall, this study showed that the adverse effects of skipping breakfast (higher insulin and FFA responses to lunch, increased hunger, and decreased satiety) were found primarily in habitual breakfast eaters. This suggests that meal skipping may have enhanced effects in habitual Eaters due to entrainment of metabolic and appetitive regulatory systems.

Indexed as

BreakfastAdultArea Under CurveBlood GlucoseCross-Over StudiesEnergy IntakeEnergy MetabolismFatty Acids, NonesterifiedFeeding BehaviorFemaleHumansInsulinOverweightPostprandial PeriodBlood GlucoseFatty Acids, NonesterifiedInsulin

Identifiers

PMID25755093
PMCPMC4380779

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.