Trial reportAnnals of family medicine2015
Long-term effect of population screening for diabetes on cardiovascular morbidity, self-rated health, and health behavior.
Trial report in Annals of family medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Screening for type 2 diabetes mellitus.The Cochrane database of systematic reviews · 2020Pooled it
- General health checks in adults for reducing morbidity and mortality from disease.The Cochrane database of systematic reviews · 2019Pooled it
- Effect of Digital Tools on the Knowledge and Performance of Frontline Health Workers For Diabetes Control in Myanmar: Cost-Effective Analysis and Quasi Experimental Study.JMIR nursing · 2025Article
- Evaluation of a Diabetes Screening Clinical Decision Support Tool.AJPM focus · 2024Article
- Improving Diabetes Screening in the Primary Care Clinic.Joint Commission journal on quality and patient safety · 2023Article
- Association of prior outpatient diabetes screening with cardiovascular events and mortality among people with incident diabetes: a population-based cohort study.Cardiovascular diabetology · 2023Article
- Non-laboratory-based risk assessment model for case detection of diabetes mellitus and pre-diabetes in primary care.Journal of diabetes investigation · 2022Article
- Observational
- Screening for Diabetes and Prediabetes.Endocrinology and metabolism clinics of North America · 2021Review
- Identifying contexts and mechanisms in multiple behavior change interventions affecting smoking cessation success: a rapid realist review.BMC public health · 2020Review
- Self-Rated Health and Glycemic Control in Type 2 Diabetes: Race by Gender Differences.Journal of racial and ethnic health disparities · 2018Article
- Article
- Article
- In this issue: developing and amplifying the effectiveness of the primary care workforce.Annals of family medicine · 2015Article
Corrections and comments
- Commented on by
Authors and funding
7 authors.
Funding
Abstract
purposeThere is limited trial evidence concerning the long-term effects of screening for type 2 diabetes on population morbidity. We examined the effect of a population-based diabetes screening program on cardiovascular morbidity, self-rated health, and health-related behaviors.
methodsWe conducted a pragmatic, parallel-group, cluster-randomized controlled trial of diabetes screening (the ADDITION-Cambridge study) including 18,875 individuals aged 40 to 69 years at high risk of diabetes in 32 general practices in eastern England (27 practices randomly allocated to screening, 5 to no-screening for control). Of those eligible for screening, 466 (2.9%) were diagnosed with diabetes. Seven years after randomization, a random sample of patients was sent a postal questionnaire: 15% from the screening group (including diabetes screening visit attenders and non-attenders) and 40% from the no-screening control group. Self-reported cardiovascular morbidity, self-rated health (using the SF-8 Health Survey and EQ-5D instrument), and health behaviors were compared between trial groups using an intention-to-screen analysis.
resultsOf the 3,286 questionnaires mailed out, 1,995 (61%) were returned, with 1,945 included in the analysis (screening: 1,373; control: 572). At 7 years, there were no significant differences between the screening and control groups in the proportion of participants reporting heart attack or stroke (OR = 0.90, 95% CI, 0.71-1.15); SF-8 physical health summary score as an indicator of self-rated health status (β -0.33, 95% CI, -1.80 to 1.14); EQ-5D visual analogue score (β: 0.80, 95% CI, -1.28 to 2.87); total physical activity (β 0.50, 95% CI, -4.08 to 5.07); current smoking (OR 0.97, 95% CI, 0.72 to 1.32); and alcohol consumption (β 0.14, 95% CI, -1.07 to 1.35).
conclusionsInvitation to screening for type 2 diabetes appears to have limited impact on population levels of cardiovascular morbidity, self-rated health status, and health behavior after 7 years.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.