Evidence map›Paper›PMID 25754367›Full record

ArticleUltrasonography (Seoul, Korea)2015

Blood flow in intracranial aneurysms treated with Pipeline embolization devices: computational simulation and verification with Doppler ultrasonography on phantom models.

Anderson Chun On Tsang, Simon Sui Man Lai, Wai Choi Chung, Abraham Yik Sau Tang, Gilberto Ka Kit Leung, Alexander Kai Kei Poon, Alfred Cheuk Hang Yu, Kwok Wing Chow

Open access · diamondAbstract read
In one paragraph

Article in Ultrasonography (Seoul, Korea), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Assessing the aneurysm occlusion efficacy of a shear-thinning biomaterial in a 3D-printed model.Journal of the mechanical behavior of biomedical materials · 2022
    Article
  5. Article
  6. Article
  7. Article
  8. 2D parametric contrast time-density analysis for the prediction of complete aneurysm occlusion at six months' post-flow diversion stent.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2020
    Article
  9. Article
  10. Aneurysm size and the Windkessel effect: An analysis of contrast intensity in digital subtraction angiography.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2017
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Anderson Chun On TsangDepartment of Surgery, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong.ORCID 0000-0003-2758-3253
Simon Sui Man LaiDepartments of Electrical and Electronic Engineering, University of Hong Kong, Hong Kong.ORCID 0000-0003-4336-1095
Wai Choi ChungDepartments of Mechanical Engineering, University of Hong Kong, Hong Kong.ORCID 0000-0002-9002-8597
Abraham Yik Sau TangDepartments of Mechanical Engineering, University of Hong Kong, Hong Kong.ORCID 0000-0001-8842-9335
Gilberto Ka Kit LeungDepartment of Surgery, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong.ORCID 0000-0003-3147-3057
Alexander Kai Kei PoonDepartments of Electrical and Electronic Engineering, University of Hong Kong, Hong Kong.ORCID 0000-0002-3958-8396
Alfred Cheuk Hang YuDepartments of Electrical and Electronic Engineering, University of Hong Kong, Hong Kong.ORCID 0000-0002-8604-0219
Kwok Wing ChowDepartments of Mechanical Engineering, University of Hong Kong, Hong Kong.ORCID 0000-0001-8763-2649
Hong Kong University of Science and Technology · HKUniversity of Hong Kong · HKHKU-Pasteur Research Pole · HK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this study was to validate a computational fluid dynamics (CFD) simulation of flow-diverter treatment through Doppler ultrasonography measurements in patient-specific models of intracranial bifurcation and side-wall aneurysms.

methodsComputational and physical models of patient-specific bifurcation and sidewall aneurysms were constructed from computed tomography angiography with use of stereolithography, a three-dimensional printing technology. Flow dynamics parameters before and after flow-diverter treatment were measured with pulse-wave and color Doppler ultrasonography, and then compared with CFD simulations.

resultsCFD simulations showed drastic flow reduction after flow-diverter treatment in both aneurysms. The mean volume flow rate decreased by 90% and 85% for the bifurcation aneurysm and the side-wall aneurysm, respectively. Velocity contour plots from computer simulations before and after flow diversion closely resembled the patterns obtained by color Doppler ultrasonography.

conclusionThe CFD estimation of flow reduction in aneurysms treated with a flow-diverting stent was verified by Doppler ultrasonography in patient-specific phantom models of bifurcation and side-wall aneurysms. The combination of CFD and ultrasonography may constitute a feasible and reliable technique in studying the treatment of intracranial aneurysms with flow-diverting stents.

Indexed as

Endovascular proceduresFlow diverterIntracranial aneurysmPrinting, three-dimensionalUltrasonography

Identifiers

PMID25754367
PMCPMC4372715
OpenAlexW1999266060

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.