Evidence map›Paper›PMID 25754083›Full record

ArticleMolecular psychiatry2016

Genetic link between family socioeconomic status and children's educational achievement estimated from genome-wide SNPs.

E Krapohl, R Plomin

Abstract readTwin Study
In one paragraph

Article in Molecular psychiatry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

71 citing papers in PubMed.

  1. Article
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  7. Where you live matters: visualizing environmental effects on reading attainment.Journal of child psychology and psychiatry, and allied disciplines · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Genetic contributions of noncognitive skills to academic development.bioRxiv : the preprint server for biology · 2023
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Assessing the impact of environmental factors on the adolescent brain: the importance of regional analyses and genetic controls.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2022
    Article
  17. Article
  18. A polygenic score for educational attainment partially predicts voter turnout.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  19. Article
  20. Estimating genetic nurture with summary statistics of multigenerational genome-wide association studies.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article

11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

E KrapohlKing's College London, MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, London, UK.
R PlominKing's College London, MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, London, UK.

Funding

Genetics, School environments and cognitive developmentR01HD044454 · NICHD · KING'S COLLEGE LONDON · PI PLOMIN, ROBERT · 2005 to 2014
$3.4M
Genetics of Mathematical Cognition and DisabilitiesR01HD059215 · NICHD · OHIO STATE UNIVERSITY · PI PETRILL, STEPHEN A. · 2009 to 2012
$2.4M
Medical Research Council G0500079Medical Research Council G0901245Medical Research Council G19/2NICHD NIH HHS HD044454NICHD NIH HHS HD059215NICHD NIH HHS R01 HD044454NICHD NIH HHS R01 HD059215
6 · The paper itself

Abstract

One of the best predictors of children's educational achievement is their family's socioeconomic status (SES), but the degree to which this association is genetically mediated remains unclear. For 3000 UK-representative unrelated children we found that genome-wide single-nucleotide polymorphisms could explain a third of the variance of scores on an age-16 UK national examination of educational achievement and half of the correlation between their scores and family SES. Moreover, genome-wide polygenic scores based on a previously published genome-wide association meta-analysis of total number of years in education accounted for ~3.0% variance in educational achievement and ~2.5% in family SES. This study provides the first molecular evidence for substantial genetic influence on differences in children's educational achievement and its association with family SES.

Indexed as

Educational StatusFamilySocial ClassAdolescentChildChild, PreschoolFemaleGenome-Wide Association StudyGenotypeHumansIntelligenceMaleMultifactorial InheritanceOligonucleotide Array Sequence AnalysisPolymorphism, Single NucleotideUnited Kingdom

Identifiers

PMID25754083
PMCPMC4486001

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.