ArticleNature communications2015
Neutral particle mass spectrometry with nanomechanical systems.
Article in Nature communications, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
42 citing papers in PubMed.
- Evaluation of Surface Acoustic Wave Nebulization for NEMS Mass Spectrometry.Journal of mass spectrometry : JMS · 2026Article
- Multiparametric quantification of bacterial cells using digital holographic microscopy.Scientific reports · 2025Article
- Dip-in Nanomechanical Probes for Mass Characterization of Nanoparticles in Ultra-Low Volume Liquid Suspensions.Small (Weinheim an der Bergstrasse, Germany) · 2025Article
- Mass and stiffness sensing performance of nanomechanical resonators: viability of infectious virus detection.Discover nano · 2025Article
- Diamond Molecular Balance: Ultra-Wide Range Nanomechanical Mass Spectrometry from MDa to TDa.Nano letters · 2025Article
- Data-driven fingerprint nanoelectromechanical mass spectrometry.Nature communications · 2024Article
- Nanomechanical mass measurements through feature-based time series clustering.The Review of scientific instruments · 2024Article
- Atmospheric-Pressure Mass Spectrometry by Single-Mode Nanoelectromechanical Systems.Nano letters · 2023Article
- Square Membrane Resonators Supporting Degenerate Modes of Vibration for High-Throughput Mass Spectrometry of Single Bacterial Cells.ACS sensors · 2023Article
- Beating thermal noise in a dynamic signal measurement by a nanofabricated cavity optomechanical sensor.Science advances · 2023Article
- Subcellular omics: a new frontier pushing the limits of resolution, complexity and throughput.Nature methods · 2023Article
- Graphene nano-electromechanical mass sensor with high resolution at room temperature.iScience · 2023Article
- Time-Resolved Imaging of High Mass Proteins and Metastable Fragments Using Matrix-Assisted Laser Desorption/Ionization, Axial Time-of-Flight Mass Spectrometry, and TPX3CAM.Analytical chemistry · 2023Article
- Compact and modular system architecture for a nano-resonator-mass spectrometer.Frontiers in chemistry · 2023Article
- A Piezoelectrically Excited ZnO Nanowire Mass Sensor with Closed-Loop Detection at Room Temperature.Micromachines · 2022Article
- Apodization Specific Fitting for Improved Resolution, Charge Measurement, and Data Analysis Speed in Charge Detection Mass Spectrometry.Journal of the American Society for Mass Spectrometry · 2022Article
- Optomechanical measurement of single nanodroplet evaporation with millisecond time-resolution.Nature communications · 2022Article
- Recent Advances in Nanomechanical Membrane-Type Surface Stress Sensors towards Artificial Olfaction.Biosensors · 2022Review
- Review
- Nano-optomechanical Resonators for Sensitive Pressure Sensing.ACS applied materials & interfaces · 2022Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
Current approaches to mass spectrometry (MS) require ionization of the analytes of interest. For high-mass species, the resulting charge state distribution can be complex and difficult to interpret correctly. Here, using a setup comprising both conventional time-of-flight MS (TOF-MS) and nano-electromechanical systems-based MS (NEMS-MS) in situ, we show directly that NEMS-MS analysis is insensitive to charge state: the spectrum consists of a single peak whatever the species' charge state, making it significantly clearer than existing MS analysis. In subsequent tests, all the charged particles are electrostatically removed from the beam, and unlike TOF-MS, NEMS-MS can still measure masses. This demonstrates the possibility to measure mass spectra for neutral particles. Thus, it is possible to envisage MS-based studies of analytes that are incompatible with current ionization techniques and the way is now open for the development of cutting-edge system architectures with unique analytical capability.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.