Evidence map›Paper›PMID 25753385›Full record

ArticleMagnetic resonance in medicine2016

Free-breathing, motion-corrected, highly efficient whole heart T2 mapping at 3T with hybrid radial-cartesian trajectory.

Hsin-Jung Yang, Behzad Sharif, Jianing Pang, Avinash Kali, Xiaoming Bi, Ivan Cokic, Debiao Li, Rohan Dharmakumar

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Article
  2. Article
  3. T2 mapping in myocardial disease: a comprehensive review.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2022
    Review
  4. Recent advances in PET-MRI for cardiac sarcoidosis.Frontiers in nuclear medicine · 2022
    Review
  5. Review
  6. Article
  7. Article
  8. Respiratory Motion-Registered Isotropic Whole-Heart TFrontiers in cardiovascular medicine · 2021
    Article
  9. Article
  10. Hybrid PET/MR imaging in myocardial inflammation post-myocardial infarction.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020
    Review
  11. 3D Whole-heart free-breathing qBOOST-T2 mapping.Magnetic resonance in medicine · 2020
    Article
  12. Review
  13. Article
  14. Accelerated free-breathing whole-heart 3D TMagnetic resonance in medicine · 2020
    Article
  15. Review
  16. Article
  17. Article
  18. Black blood myocardial TMagnetic resonance in medicine · 2019
    Article
  19. A multi-band double-inversion radial fast spin-echo technique for T2 cardiovascular magnetic resonance mapping of the heart.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2018
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hsin-Jung YangBiomedical Imaging Research Institute, Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Behzad SharifBiomedical Imaging Research Institute, Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Jianing PangBiomedical Imaging Research Institute, Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Avinash KaliBiomedical Imaging Research Institute, Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Xiaoming BiMR R&D, Siemens Healthcare, Los Angeles, California, USA.
Ivan CokicBiomedical Imaging Research Institute, Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Debiao LiBiomedical Imaging Research Institute, Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Rohan DharmakumarBiomedical Imaging Research Institute, Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California, USA.

Funding

Reliable Evaluation of Coronary Artery Disease using Myocardial BOLD MRI with CO2R01HL091989 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI DHARMAKUMAR, ROHAN · 2008 to 2016
$3.5M
NHLBI NIH HHS HL091989NHLBI NIH HHS R01 HL091989
6 · The paper itself

Abstract

purposeTo develop and test a time-efficient, free-breathing, whole heart T2 mapping technique at 3.0T.

methodsECG-triggered three-dimensional (3D) images were acquired with different T2 preparations at 3.0T during free breathing. Respiratory motion was corrected with a navigator-guided motion correction framework at near perfect efficiency. Image intensities were fit to a monoexponential function to derive myocardial T2 maps. The proposed 3D, free breathing, motion-corrected (3D-FB-MoCo) approach was studied in ex vivo canine hearts and kidneys, healthy volunteers, and canine subjects with acute myocardial infarction (AMI).

resultsEx vivo T2 values from proposed 3D T2 -prep gradient echo were not different from two-dimensional (2D) spin echo (P = 0.7) and T2 -prep balanced steady-state free precession (bSSFP) (P = 0.7). In healthy volunteers, compared with 3D-FB-MoCo and breath-held 2D T2 -prep bSSFP (2D-BH), non-motion-corrected (3D-FB-Non-MoCo) myocardial T2 was longer, had a larger coefficient of variation (COV), and had a lower image quality (IQ) score (T2 = 40.3 ms, COV = 38%, and IQ = 2.3; all P < 0.05). Conversely, the mean and COV and IQ of 3D-FB-MoCo (T2 = 37.7 ms, COV = 17%, and IQ = 3.5) and 2D-BH (T2 = 38.0 ms, COV = 15%, and IQ = 3.8) were not different (P = 0.99, P = 0.74, and P = 0.14, respectively). In AMI, T2 values and edema volumes from 3D-FB-MoCo and 2D-BH were closely correlated (R(2) = 0.88 and 0.96, respectively).

conclusionThe proposed whole heart T2 mapping approach can be performed within 5 min with similar accuracy to that of the 2D-BH T2 mapping approach.

Indexed as

ArtifactsAlgorithmsAnimalsCardiac-Gated Imaging TechniquesDogsHumansImage EnhancementImage Interpretation, Computer-AssistedImaging, Three-DimensionalMagnetic Resonance Imaging, CineMotionMyocardial InfarctionMyocardiumRespiratory Mechanicscardiac BOLD MRIcardiac T2 mappingfast imagingmyocardial edema

Identifiers

PMID25753385
PMCPMC4561222

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.