ArticleScientific reports2015
Photothermal cellular stimulation in functional bio-polymer interfaces.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
63 citing papers in PubMed, 167 citations in OpenAlex.
- Amplitude-controllable event-driven organic photosensors based on ionic-mediated inhibition.Nature materials · 2026Article
- Spatially Resolved Photostimulation of Cardiac Activity Using Optoelectronic Peptides.ACS central science · 2026Article
- Blood-catalyzed n-doped polymers for reversible optical neural control.Science (New York, N.Y.) · 2026Article
- Metasurface-assisted bioelectronics: bridging photonic innovation with biomedical implants.Light, science & applications · 2025Article
- The Impact of Physical Form on the Biocompatibility of Poly(3-hexylthiophene-2,5-diyl).Materials (Basel, Switzerland) · 2025Article
- Neural vs Neuromorphic Interfaces: Where Are We Standing?Chemical reviews · 2025Review
- Micropatterning Photoconductive Peptide Assemblies on Stiff and Soft Biomaterial Substrates.ACS applied materials & interfaces · 2025Article
- Organic Bioelectronics in Microphysiological Systems: Bridging the Gap Between Biological Systems and Electronic Technologies.Biosensors · 2025Review
- Ultrathin rubbery bio-optoelectronic stimulators for untethered cardiac stimulation.Science advances · 2024Article
- A silicon diode-based optoelectronic interface for bidirectional neural modulation.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Capacitive and Efficient Near-Infrared Stimulation of Neurons via an Ultrathin AgBiSACS applied materials & interfaces · 2024Article
- A biodegradable and flexible neural interface for transdermal optoelectronic modulation and regeneration of peripheral nerves.Nature communications · 2024Article
- Nanoparticle-based optical interfaces for retinal neuromodulation: a review.Frontiers in cellular neuroscience · 2024Review
- Enhanced organic photovoltaic-based retinal prosthesis using a cathode-modified structure with plasmonic silver nanoparticles: a computational study.Frontiers in cellular neuroscience · 2024Article
- Photo-Chemical Stimulation of Neurons with Organic Semiconductors.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Article
- Modulation of Mechanosensitive Potassium Channels by a Membrane-targeted Nongenetic Photoswitch.The journal of physical chemistry. B · 2023Article
- Semiconducting Polymer Nanoporous Thin Films as a Tool to Regulate Intracellular ROS Balance in Endothelial Cells.ACS applied materials & interfaces · 2023Article
- Light-triggered cardiac microphysiological model.APL bioengineering · 2023Article
- Bioresorbable thin-film silicon diodes for the optoelectronic excitation and inhibition of neural activities.Nature biomedical engineering · 2023Article
- Optical modulation of excitation-contraction coupling in human-induced pluripotent stem cell-derived cardiomyocytes.iScience · 2023Article
3 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
Hybrid interfaces between organic semiconductors and living tissues represent a new tool for in-vitro and in-vivo applications, bearing a huge potential, from basic researches to clinical applications. In particular, light sensitive conjugated polymers can be exploited as a new approach for optical modulation of cellular activity. In this work we focus on light-induced changes in the membrane potential of Human Embryonic Kidney (HEK-293) cells grown on top of a poly(3-hexylthiophene) (P3HT) thin film. On top of a capacitive charging of the polymer interface, we identify and fully characterize two concomitant mechanisms, leading to membrane depolarization and hyperpolarisation, both mediated by a thermal effect. Our results can be usefully exploited in the creation of a new platform for light-controlled cell manipulation, with possible applications in neuroscience and medicine.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.