Evidence map›Paper›PMID 25752885›Full record

Trial reportSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2015

Quality-of-life outcomes in patients with gynecologic cancer referred to integrative oncology treatment during chemotherapy.

Eran Ben-Arye, Noah Samuels, Elad Schiff, Orit Gressel Raz, Ilanit Shalom Sharabi, Ofer Lavie

Open access · bronzeAbstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
17.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 40 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Integrative Medicine for Ovarian Cancer.Current oncology reports · 2023
    Review
  6. Article
  7. Can integrative oncology increase adherence to chemotherapy in advanced gynecologic cancer?Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Article
  8. Correlation between an integrative oncology treatment program and survival in patients with advanced gynecological cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
    Article
  9. Article
  10. Inverse relationship between reduced fatigue and severity of anemia in oncology patients treated with integrative medicine: understanding the paradox.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2018
    Article
  11. Article
  12. Article
  13. Article
  14. Impact of a complementary/integrative medicine program on the need for supportive cancer care-related medications.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2017
    Article
  15. Article
  16. Article
  17. Quality of life-related outcomes from a patient-tailored integrative medicine program: experience of Russian-speaking patients with cancer in Israel.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2016
    Article
  18. Designing an integrative gynecologic oncology model of supportive care: call for a cross-cultural international collaboration.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2016
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Eran Ben-AryeIntegrative Oncology Program, The Oncology Service, Lin Medical Center, Western Galilee District, Clalit Health Services, 35 Rothschild St., Haifa, Israel. eranben@netvision.net.il.
Noah SamuelsIntegrative Oncology Program, The Oncology Service, Lin Medical Center, Western Galilee District, Clalit Health Services, 35 Rothschild St., Haifa, Israel.
Elad SchiffDepartment of Internal Medicine and Integrative Surgery Service, Bnai Zion Hospital, Haifa, Israel.
Orit Gressel RazIntegrative Oncology Program, The Oncology Service, Lin Medical Center, Western Galilee District, Clalit Health Services, 35 Rothschild St., Haifa, Israel.
Ilanit Shalom SharabiIntegrative Oncology Program, The Oncology Service, Lin Medical Center, Western Galilee District, Clalit Health Services, 35 Rothschild St., Haifa, Israel.
Ofer LavieDepartment of Obstetrics and Gynecology, Gynecologic Oncology Service, Carmel Medical Center, Haifa, Israel.
Clalit Health Services · ILBnai Zion Medical Center · ILCarmel Medical Center · ILTechnion – Israel Institute of Technology · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveIntegrative oncology incorporates complementary medicine (CM) therapies in patients with cancer. We explored the impact of an integrative oncology therapeutic regimen on quality-of-life (QOL) outcomes in women with gynecological cancer undergoing chemotherapy. PATIENTS AND

methodsA prospective preference study examined patients referred by oncology health care practitioners (HCPs) to an integrative physician (IP) consultation and CM treatments. QOL and chemotherapy-related toxicities were evaluated using the Edmonton Symptom Assessment Scale (ESAS) and Measure Yourself Concerns and Wellbeing (MYCAW) questionnaire, at baseline and at a 6-12-week follow-up assessment. Adherence to the integrative care (AIC) program was defined as ≥ 4 CM treatments, with ≤ 30 days between each session.

resultsOf 128 patients referred by their HCP, 102 underwent IP consultation and subsequent CM treatments. The main concerns expressed by patients were fatigue (79.8%), gastrointestinal symptoms (64.6%), pain and neuropathy (54.5 %), and emotional distress (45.5%). Patients in both AIC (n = 68) and non-AIC (n = 28) groups shared similar demographic, treatment, and cancer-related characteristics. ESAS fatigue scores improved by a mean of 1.97 points in the AIC group on a scale of 0-10 and worsened by a mean of 0.27 points in the non-AIC group (p = 0.033). In the AIC group, MYCAW scores improved significantly (p < 0.0001) for each of the leading concerns as well as for well-being, a finding which was not apparent in the non-AIC group.

conclusionsAn IP-guided CM treatment regimen provided to patients with gynecological cancer during chemotherapy may reduce cancer-related fatigue and improve other QOL outcomes.

Indexed as

Complementary TherapiesIntegrative MedicineQuality of LifeAdultAgedAntineoplastic Combined Chemotherapy ProtocolsFatigueFemaleGenital Neoplasms, FemaleHumansMiddle AgedPain ManagementProspective StudiesSurveys and QuestionnairesSymptom AssessmentTreatment OutcomeChemotherapyComplementary medicineGynecologic oncologyIntegrative medicineQuality of life

Identifiers

PMID25752885
OpenAlexW2124588749

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.