Evidence map›Paper›PMID 25752834›Full record

ArticleNature reviews. Nephrology2015

Nephrotic syndrome: Efficacy of rituximab in challenging nephrotic syndrome.

Kevin V Lemley, Robert H Mak

Abstract readNewsComment
PubMed Publisher
In one paragraph

Article in Nature reviews. Nephrology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Kevin V LemleyDivision of Paediatric Nephrology, Children's Hospital Los Angeles, University of Southern California, 4650 Sunset Boulevard, Los Angeles, CA 90027, USA.
Robert H MakDivision of Paediatric Nephrology, Rady Children's Hospital, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0630, USA.
Children's Hospital of Los Angeles · USRady Children's Hospital-San Diego · US

Funding

National Center for Muscle Rehabilitation ResearchR24HD050837 · NICHD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LIEBER, RICHARD L., WARD, SAMUEL RICHARD · 2005 to 2014
$7.2M
NICHD NIH HHS R24HD050837NIDDK NIH HHS U01DK‑03,012
6 · The paper itself

Abstract

A new trial provides further evidence that rituximab treatment can reduce the risk of relapse in children with steroid-dependent idiopathic nephrotic syndrome. Addition of a single infusion of rituximab to steroid therapy was associated with a decrease in proteinuria at 3 months and a significant increase in the relapse-free period.

Indexed as

Anti-Inflammatory AgentsImmunologic FactorsNephrotic SyndromePrednisoneRituximabFemaleHumansMaleRandomized Controlled Trials as TopicAnti-Inflammatory AgentsImmunologic FactorsPrednisoneRituximab

Identifiers

PMID25752834
OpenAlexW2041581457

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.