Evidence map›Paper›PMID 25752563›Full record

GuidelineThe Lancet. Oncology2015

Recommendations for cardiomyopathy surveillance for survivors of childhood cancer: a report from the International Late Effects of Childhood Cancer Guideline Harmonization Group.

Saro H Armenian, Melissa M Hudson, Renee L Mulder, Ming Hui Chen, Louis S Constine, Mary Dwyer, Paul C Nathan, Wim J E Tissing, Sadhna Shankar, Elske Sieswerda and 8 more

Abstract readPractice GuidelineReview
PubMed Full text at PMC Publisher
In one paragraph

Guideline in The Lancet. Oncology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 254 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
254citing papers in PubMed, 9 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

254 citing papers in PubMed, 9 syntheses or guidelines pooled it.

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194 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Saro H ArmenianDepartment of Population Sciences, City of Hope, Duarte, USA. Electronic address: sarmenian@coh.org.
Melissa M HudsonDepartments of Oncology and Epidemiology and Cancer Control, St Jude Children's Research Hospital, Memphis, TN, USA.
Renee L MulderDepartment of Pediatric Oncology, Emma Children's Hospital/Academic Medical Centre, Amsterdam, Netherlands.
Ming Hui ChenDepartment of Pediatrics, Boston Children's Hospital and Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
Louis S ConstineDepartments of Radiation Oncology and Pediatrics, University of Rochester Medical Center, Rochester, NY, USA.
Mary DwyerPeter MacCallum Cancer Centre, East Melbourne, VIC, Australia.
Paul C NathanThe Hospital for Sick Children and the University of Toronto, Department of Pediatrics and Institute of Health Policy, Management and Evaluation, Toronto, ON, Canada.
Wim J E TissingDivision of Pediatric Oncology and Pediatric Hematology, Beatrix Children's Hospital, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.
Sadhna ShankarDivision of Oncology, Center for Cancer and Blood Disorders, Children's National Medical Center, Washington, DC, USA.
Elske SieswerdaDepartment of Pediatric Oncology, Emma Children's Hospital/Academic Medical Centre, Amsterdam, Netherlands.
Rod SkinnerDepartment of Paediatric and Adolescent Haematology/Oncology, Great North Children's Hospital and University of Newcastle, Newcastle upon Tyne, UK.
Julia SteinbergerDepartment of Pediatrics, Division of Cardiology, University of Minnesota Amplatz Childrens' Hospital, Minneapolis, MN, USA.
Elvira C van DalenDepartment of Pediatric Oncology, Emma Children's Hospital/Academic Medical Center, Amsterdam, the Netherlands.
Helena van der PalDepartment of Pediatric Oncology and Medical Oncology, Emma Children's Hospital/Academic Medical Centre, Amsterdam, Netherlands.
W Hamish WallaceDepartment of Hematology/Oncology, Royal Hospital for Sick Children, Edinburgh, Scotland.
Gill LevittDepartment of Oncology/Haematology, Great Ormond Street Hospital for Children NHS Trust, London, UK.
Leontien C M KremerDepartment of Pediatric Oncology, Emma Children's Hospital/Academic Medical Centre, Amsterdam, Netherlands.
International Late Effects of Childhood Cancer Guideline Harmonization Group

Funding

COG FOREIGN ACCRUALU10CA098543 · NCI · NATIONAL CHILDHOOD CANCER FOUNDATION · PI ADAMSON, PETER C. · 2003 to 2013
$335.5M
Viral Vector Technology (VVTSR)P30CA021765 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI GERARD PAUL ZAMBETTI · 1985 to 2026
$166.9M
Oncology Research Career Development ProgramK12CA001727 · NCI · CITY OF HOPE NATIONAL MEDICAL CENTER · PI MORTIMER, JOANNE E. · 1992 to 2024
$14.6M
Cardiovascular Risk and Insulin Resistance: Age 7-40R01DK072124 · NIDDK · UNIVERSITY OF MINNESOTA · PI STEINBERGER, JULIA · 2007 to 2011
$3.0M
Metabolic Syndrome in Childhood Cancer SurvivorsR01CA113930 · NCI · UNIVERSITY OF MINNESOTA · PI STEINBERGER, JULIA · 2006 to 2010
$2.5M
NCI NIH HHS 1R01CA113930NCI NIH HHS 1 U10 CA098543NCI NIH HHS 2 K12 CA001727-14NCI NIH HHS CA 21765NCI NIH HHS K12 CA001727NCI NIH HHS P30 CA021765NCI NIH HHS R01 CA113930NCI NIH HHS U10 CA098543NIDDK NIH HHS 1R01DK072124NIDDK NIH HHS R01 DK072124
6 · The paper itself

Abstract

Survivors of childhood cancer treated with anthracycline chemotherapy or chest radiation are at an increased risk of developing congestive heart failure. In this population, congestive heart failure is well recognised as a progressive disorder, with a variable period of asymptomatic cardiomyopathy that precedes signs and symptoms. As a result, several clinical practice guidelines have been developed independently to help with detection and treatment of asymptomatic cardiomyopathy. These guidelines differ with regards to definitions of at-risk populations, surveillance modality and frequency, and recommendations for interventions. Differences between these guidelines could hinder the effective implementation of these recommendations. We report on the results of an international collaboration to harmonise existing cardiomyopathy surveillance recommendations using an evidence-based approach that relied on standardised definitions for outcomes of interest and transparent presentation of the quality of the evidence. The resultant recommendations were graded according to the quality of the evidence and the potential benefit gained from early detection and intervention.

Indexed as

SurvivorsAdultAge FactorsAnthracyclinesAntibiotics, AntineoplasticBiomarkersCardiomyopathiesChildChild, PreschoolConsensusCooperative BehaviorDiagnostic ImagingEarly DiagnosisEchocardiographyEvidence-Based MedicineHumansAnthracyclinesAntibiotics, AntineoplasticBiomarkers

Identifiers

PMID25752563
PMCPMC4485458

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.