ArticleInternational journal of bacteriology
Modulation of Bacterial Multidrug Resistance Efflux Pumps of the Major Facilitator Superfamily.
Article in International journal of bacteriology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
65 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Antimicrobial resistance in fish and poultry: Public health implications for animal source food production in Nigeria, Egypt, and South Africa.Frontiers in antibiotics · 2022Pooled it
- Efflux modulation as an antimicrobial strategy: mechanisms and translational perspectives.npj drug discovery · 2026Review
- Biodegradation Characteristics of Piperacillin by Marine Bacillus cereus PP1 and Genome-Guided Mining of Candidate β-Lactamases.Functional & integrative genomics · 2026Article
- Genes and physiological strategies in bacterial antibiotic resistance.Frontiers in microbiology · 2026Review
- Bacterial mutation dynamics emerging insights into virulence evolution and drug resistance. A review study.Frontiers in medicine · 2026Review
- Advances in Antimicrobial Applications of Ag, Cu, and AgCu Nanoparticle-Doped Polymeric Composite Materials: A Comprehensive Review.ACS nano · 2025Review
- Algal Metabolites as Novel Therapeutics Against Methicillin-ResistantPharmaceutics · 2025Review
- Small-molecule strategies to combat antibiotic resistance: mechanisms, modifications, and contemporary approaches.RSC advances · 2025Review
- Anti-virulence effects of Diclofenac sodium in combination with gentamicin on Pseudomonas aeruginosa: attenuation of quorum sensing related traits and efflux pump systems.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025Article
- The Invisible Threat of Antibiotic Resistance in Food.Antibiotics (Basel, Switzerland) · 2025Review
- Genetic determinants of silver nanoparticle resistance and the impact of gamma irradiation on nanoparticle stability.BMC microbiology · 2025Article
- Exogenous plasmid capture to characterize tetracycline-resistance plasmids in sprouts obtained from retail in Germany.Frontiers in microbiology · 2025Article
- Reviewing the Therapeutic Potential of Plant-based Natural Products against Multidrug-resistant Bacteria (MDR).Current drug research reviews · 2025Review
- Strategies to Overcome Antimicrobial Resistance in Nosocomial Infections, A Review and Update.Infectious disorders drug targets · 2024Review
- Antibiotic persistence and its impact on the environment.3 Biotech · 2023Review
- The role of efflux pumps ın antıbıotıc resıstance of gram negatıve rods.Archives of microbiology · 2023Review
- Quaternary ammonium disinfectants and antiseptics: tolerance, resistance and potential impact on antibiotic resistance.Antimicrobial resistance and infection control · 2023Review
- The Two-Component System CpxRA Affects Antibiotic Susceptibility and Biofilm Formation in Avian PathogenicAnimals : an open access journal from MDPI · 2023Article
- Estimating the optimal efflux inhibitor concentration of carvacrol as a function of the bacterial physiological state.Frontiers in microbiology · 2023Article
- Mechanistic insights into nanoparticle surface-bacterial membrane interactions in overcoming antibiotic resistance.Frontiers in microbiology · 2023Review
5 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Bacterial infections pose a serious public health concern, especially when an infectious disease has a multidrug resistant causative agent. Such multidrug resistant bacteria can compromise the clinical utility of major chemotherapeutic antimicrobial agents. Drug and multidrug resistant bacteria harbor several distinct molecular mechanisms for resistance. Bacterial antimicrobial agent efflux pumps represent a major mechanism of clinical resistance. The major facilitator superfamily (MFS) is one of the largest groups of solute transporters to date and includes a significant number of bacterial drug and multidrug efflux pumps. We review recent work on the modulation of multidrug efflux pumps, paying special attention to those transporters belonging primarily to the MFS.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.