ArticleJoints
Sports-related changes of the synovial membrane.
Article in Joints. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.
- Previous knee surgery increases risks of revision, infection, pain and stiffness after knee replacement arthroplasty: a systematic review and meta-analysis.BMC musculoskeletal disorders · 2025Pooled it
- Structural and Histomorphological Evaluation of the Stifle Joint Capsule in Canine Congenital Patellar Luxation and Cranial Cruciate Ligament Rupture.Animals : an open access journal from MDPI · 2025Article
- Chronic reactive synovitis in patients undergoing ACL reconstruction and augmentation with tape-type sutures.Journal of clinical orthopaedics and trauma · 2025Article
- Atypical Presentation of Non-Ossifying Fibroma in a Professional Muay Thai Boxer: A Case Report and a Narrative Review of the Literature.Journal of orthopaedic case reports · 2023Article
- Deep Infrapatellar Bursitis in Preadolescent Baseball Players: A Cross-Sectional Study.Orthopaedic journal of sports medicine · 2022Article
- Synovitis following anterior cruciate ligament reconstruction using the LARS device.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2019Article
- Total knee arthroplasty fibrosis following arthroscopic intervention.Annals of translational medicine · 2017Article
- Surgical management of hip prosthetic failure in metallosis: A case series and literature review.Journal of orthopaedicsReview
- Resumption of physical activity and sport after knee replacement.Journal of orthopaedicsArticle
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposethe aim of this study is to differentiate the behavior of the synovial membrane in the presence of various stimuli in patients who practice sports.
methodsfifty one patients (30 males and 21 females, mean age 48 years, range 31-59 years) who actively practiced non-competitive sports underwent a biopsy of the synovial membrane during arthroscopic surgery performed for joint effusion secondary to meniscal lesion (24 cases), anterior cruciate ligament injury (ACL) (17 cases), postoperative knee joint stiffness (2 cases), aseptic loosening or dislocation of the polyethylene component of uni-compartmental knee arthroplasty (5 cases), and anterior fibrous impingement of the ankle (3 cases). Synovial tissue samples were obtained during surgery from all the patients and processed for light microscopy, transmission electron microscopy and scanning electron microscopy observation.
resultscirculatory phenomena were observed in acute inflammatory processes, characterized by hyperemia and vasodilation. Exudative and infiltrative phenomena were observed in the presence of foreign bodies and were characterized by leukocytic exudation (presence of polynuclear neutrophils), accompanied by lymphomonocytic infiltration. Proliferative phenomena were observed in post-traumatic forms of synovitis (ACL and meniscal injuries), characterized by hypertrophy and proliferation of villous formations. Degenerative and regressive phenomena were observed in cases of fibrous reaction (ankle impingement and joint stiffness) and were characterized by formation of dense fibrous connective tissue with hyaline patches, evolving towards sclerosis.
conclusionsthe activation of inflammatory processes in patients who expose their joints to excessive stress may lead to the formation of hyperplastic tissue. Ultramicroscopic debris is usually capable of transforming the structural organization of the synovial tissue. LEVEL OF EVIDENCE: Level IV, observational case series.
Indexed as
Identifiers
25750907PMC4334218W1786471120What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.