Evidence map›Paper›PMID 25750765›Full record

ArticleCurrent nutrition reports2015

Dietary Risk Reduction Factors for the Barrett's Esophagus-Esophageal Adenocarcinoma Continuum: A Review of the Recent Literature.

Jessica L Petrick, Nan Li, Kathleen M McClain, Susan E Steck, Marilie D Gammon

Abstract read
In one paragraph

Article in Current nutrition reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jessica L PetrickDepartment of Epidemiology, 135 Dauer Drive, University of North Carolina, Chapel Hill, NC, 27599, phone: 919-966-7430, fax: 919-966-2089.
Nan LiDepartment of Epidemiology, 135 Dauer Drive, University of North Carolina, Chapel Hill, NC, 27599, phone: 919-966-7430, fax: 919-966-2089.
Kathleen M McClainDepartment of Epidemiology, 135 Dauer Drive, University of North Carolina, Chapel Hill, NC, 27599, phone: 919-966-7430, fax: 919-966-2089.
Susan E SteckDepartment of Epidemiology and Biostatistics, 915 Greene Street, University of South Carolina, Columbia, SC 29208; phone: 803-576-5638, fax: 803-576-5624.
Marilie D GammonDepartment of Epidemiology, 135 Dauer Drive, CB# 7435, University of North Carolina, Chapel Hill, NC, 27599-7435, phone: 919-966-7421, 919-966-2089.

Funding

Whole Exome Approaches for Esophageal Adenocarcinoma Susceptibility GenesU54CA163060 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI CHAK, AMITABH, GUDA, KISHORE · 2011 to 2022
$14.0M
Flavonoids, esophageal/gastric cardia adenocarcinoma and Barretts Esophagus RiskR03CA159409 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI GAMMON, MARILIE D. · 2012 to 2013
$140k
NCI NIH HHS R03 CA159409NCI NIH HHS U54 CA163060
6 · The paper itself

Abstract

Esophageal adenocarcinoma (EA) incidence is among the most rapidly increasing of any cancer type in the U.S., and prognosis is poor. Prevalence of the potential precursor lesion, Barrett's esophagus (BE), is also increasing. Candidates for safe and effective risk reduction strategies are needed, potentially including dietary components. In this qualitative review, we summarize recently published epidemiologic studies, in context of earlier work, on dietary intake and BE-EA outcomes. Potential cohort study/intervention trial candidates which could be increased to reduce BE-EA development include intake of: (1) fruits and vegetables; vegetables; fruit (EA only); (2) β-carotene and vitamins C and E; (3) folate (EA only); and (4) total fiber (EA only). Also, (5) red and processed meat intake could be targeted for dietary reduction/omission to reduce EA development. Few dietary constituents have been evaluated among EA patients to examine associations with mortality, thus interventions conducted among EA patients are premature.

Indexed as

Barrett's esophagusdietary intakeepidemiologyesophageal adenocarcinomafolatefruitsnutritionred meatsurvivorshiptotal fibervegetablesvitamin Cvitamin Eβ-carotene

Identifiers

PMID25750765
PMCPMC4349493

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.