Evidence map›Paper›PMID 25750739›Full record

ReviewF1000prime reports2015

Empiric/pre-emptive anti-Candida therapy in non-neutropenic ICU patients.

Jean-François Timsit, Sarah Chemam, Sébastien Bailly

Open access · diamondAbstract readReview
In one paragraph

Review in F1000prime reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Jean-François TimsitINSERM IAME, UMR 1137, F-75018 Paris France ; Paris Diderot University IAME, UMR 1137, Sorbonne Paris Cité, F-75018 Paris France ; AP-HP, Bichat Hospital, medical and infectious diseases ICU F-75018 Paris France.
Sarah ChemamAP-HP, Bichat Hospital, medical and infectious diseases ICU F-75018 Paris France.
Sébastien BaillyINSERM IAME, UMR 1137, F-75018 Paris France ; Paris Diderot University IAME, UMR 1137, Sorbonne Paris Cité, F-75018 Paris France ; Joseph Fourier (Grenoble 1) University, Albert Bonniot institute U 823, Grenoble, F-38000 France.
Inserm · FRAssistance Publique – Hôpitaux de Paris · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The potential of the systemic antifungal treatment of non-immunocompromised patients with sepsis, extra-digestive Candida colonization and multiple organ failure is unknown, although it represents three out of four antifungal treatments prescribed in intensive care units. It may allow an early treatment of invasive fungal infection at incubation phase, but exposes patients to unnecessary antifungal treatments with subsequent costs and antifungal selection pressure. As early diagnostic tests for invasive candidiasis are still considered insufficient, the potential of this strategy needs to be demonstrated by a randomized controlled trial. Such a trial is currently ongoing.

Identifiers

PMID25750739
PMCPMC4335794
OpenAlexW1996373872

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.