ArticleFrontiers in microbiology2015
Heavy metal whole-cell biosensors using eukaryotic microorganisms: an updated critical review.
Article in Frontiers in microbiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed.
- Yeast Biosensors for the Safety of Fermented Beverages.Biosensors · 2026Review
- HarnessingSensors (Basel, Switzerland) · 2025Review
- Whole Cells of Microorganisms-A Powerful Bioanalytical Tool for Measuring Integral Parameters of Pollution: A Review.Biosensors · 2025Review
- Development of a Whole-Cell System Based on the Use of Genetically Modified Protoplasts to Detect Nickel Ions in Food Matrices.International journal of molecular sciences · 2024Article
- A review of biosensor for environmental monitoring: principle, application, and corresponding achievement of sustainable development goals.Bioengineered · 2023Review
- Biological and technical challenges for implementation of yeast-based biosensors.Microbial biotechnology · 2023Review
- Genome-wide profiling of drought-tolerant Arabidopsis plants over-expressing chickpea MT1 gene reveals transcription factors implicated in stress modulation.Functional & integrative genomics · 2022Article
- Bioinformatic prediction of putative metallothioneins in non-ciliate protists.Biology letters · 2022Article
- Molecular characterization and transcriptional modulation of stress-responsive genes under heavy metal stress in freshwater ciliate, Euplotes aediculatus.Ecotoxicology (London, England) · 2022Article
- Assessment of effluents quality through ecotoxicological assays: evaluation of three wastewater treatment plants with different technologies.Environmental science and pollution research international · 2022Article
- Freshwater organisms potentially useful as biosensors and power-generation mediators in biohybrid robotics.Biological cybernetics · 2021Article
- Harnessing Solar Energy using Phototrophic Microorganisms: A Sustainable Pathway to Bioenergy, Biomaterials, and Environmental Solutions.Renewable & sustainable energy reviews · 2021Article
- A fluorescence-based yeast sensor for monitoring acetic acid.Engineering in life sciences · 2021Article
- Whole-Cell Microbial Bioreporter for Soil Contaminants Detection.Frontiers in bioengineering and biotechnology · 2021Review
- Identification of stress-responsive transcription factors with protein-bound Escherichia coli genomic DNA libraries.AMB Express · 2020Article
- Repetitive Detection of Aromatic Hydrocarbon Contaminants with Bioluminescent Bioreporters Attached on Tapered Optical Fiber Elements.Sensors (Basel, Switzerland) · 2020Article
- Yeast-Based Biosensors: Current Applications and New Developments.Biosensors · 2020Review
- New Plant Growth-Promoting, Chromium-DetoxifyingFrontiers in bioengineering and biotechnology · 2020Article
- Microalgal Metallothioneins and Phytochelatins and Their Potential Use in Bioremediation.Frontiers in microbiology · 2020Review
- Two plant-hosted whole-cell bacterial biosensors for detection of bioavailable Cr(VI).World journal of microbiology & biotechnology · 2019Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This review analyzes the advantages and disadvantages of using eukaryotic microorganisms to design whole-cell biosensors (WCBs) for monitoring environmental heavy metal pollution in soil or aquatic habitats. Basic considerations for designing a eukaryotic WCB are also shown. A comparative analysis of the promoter genes used to design WCBs is carried out, and the sensitivity and reproducibility of the main reporter genes used is also reviewed. Three main eukaryotic taxonomic groups are considered: yeasts, microalgae, and ciliated protozoa. Models that have been widely analyzed as potential WCBs are the Saccharomyces cerevisiae model among yeasts, the Tetrahymena thermophila model for ciliates and Chlamydomonas model for microalgae. The advantages and disadvantages of each microbial group are discussed, and a ranking of sensitivity to the same type of metal pollutant from reported eukaryotic WCBs is also shown. General conclusions and possible future developments of eukaryotic WCBs are reported.
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