ArticleFrontiers in psychology2015
Unifying treatments for depression: an application of the Free Energy Principle.
Article in Frontiers in psychology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
27 citing papers in PubMed.
- Disorder at the Synapse: How the Active Inference Framework Unifies Competing Perspectives on Depression.Entropy (Basel, Switzerland) · 2025Review
- How mood shapes belief updating bias in depression.Cognitive, affective & behavioral neuroscience · 2025Review
- Early maladaptive schemas from child maltreatment in depression and psychotherapeutic remediation: a predictive coding framework.Frontiers in psychiatry · 2025Review
- Editorial: Reward processing in motivational and affective disorders, volume II.Frontiers in psychology · 2025Article
- Active Inference in Psychology and Psychiatry: Progress to Date?Entropy (Basel, Switzerland) · 2024Review
- Evaluation of the Perceived Benefits of a Peer Support Group for People with Mental Health Problems.Nursing reports (Pavia, Italy) · 2024Article
- Weakened effective connectivity between salience network and default mode network during resting state in adolescent depression.Frontiers in psychiatry · 2024Article
- A link between age, affect, and predictions?European journal of ageing · 2022Review
- From Broken Models to Treatment Selection: Active Inference as a Tool to Guide Clinical Research and Practice.Clinical psychology in Europe · 2022Article
- Placebo induced expectations of mood enhancement generate a positivity effect in emotional processing.Scientific reports · 2022Article
- Action-Shapers and Their Neuro-Immunological Foundations.Frontiers in psychology · 2022Article
- Piloting the Update: The Use of Therapeutic Relationship for Change - A Free Energy Account.Frontiers in psychology · 2022Article
- Psychoanalytic psychotherapies and the free energy principle.Frontiers in human neuroscience · 2022Article
- Learned uncertainty: The free energy principle in anxiety.Frontiers in psychology · 2022Article
- Computational approaches to treatment response prediction in major depression using brain activity and behavioral data: A systematic review.Network neuroscience (Cambridge, Mass.) · 2022Article
- Alpha-to-beta- and gamma-band activity reflect predictive coding in affective visual processing.Scientific reports · 2021Article
- Harnessing the Spatial Foundation of Mind in Breaking Vicious Cycles in Anxiety, Insomnia, and Depression: The Future of Virtual Reality Therapy Applications.Frontiers in psychiatry · 2021Article
- Minds and Brains, Sleep and Psychiatry.Psychiatric research and clinical practice · 2021Review
- Attentional Control in Subclinical Anxiety and Depression: Depression Symptoms Are Associated With Deficits in Target Facilitation, Not Distractor Inhibition.Frontiers in psychology · 2020Article
- Trauma or Drama: A Predictive Processing Perspective on the Continuum of Stress.Frontiers in psychology · 2020Article
Corrections and comments
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1 author.
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No grant is acknowledged in the PubMed record.
Abstract
Major Depressive Disorder is a debilitating and increasingly prevalent psychiatric condition (Compton et al., 2006; Andersen et al., 2011). At present, its primary treatments are antidepressant medications and psychotherapy. Curiously, although the pharmacological effects of antidepressants manifest within hours, remission of clinical symptoms takes a number of weeks-if at all. Independently, support has grown for an idea-proposed as early as Helmholtz (von Helmholtz, 1924)-that the brain is a prediction machine, holding generative models for the purpose of inferring causes of sensory information (Dayan et al., 1995; Rao and Ballard, 1999; Knill and Pouget, 2004; Friston et al., 2006; Friston, 2010). If the brain does indeed represent a collection of beliefs about the causal structure of the world, then the depressed phenotype may emerge from a collection of depressive beliefs. These beliefs are modified gradually through successive combinations of expectations with observations. As a result, phenotypic remission ought to take some time as the brain's relevant statistical structures become less pessimistic.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.