Evidence map›Paper›PMID 25750609›Full record

ArticleAdvanced functional materials2010

Targeting of Cancer Cells Using Quantum Dot-Polypeptide Hybrid Assemblies that Function as Molecular Imaging Agents and Carrier Systems.

Bayu Atmaja, Bertrand H Lui, Yuhua Hu, Stayce E Beck, Curtis W Frank, Jennifer R Cochran

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced functional materials, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Nanomaterials: Synthesis and Applications in Theranostics.Nanomaterials (Basel, Switzerland) · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Bayu AtmajaDepartment of Chemical Engineering, Stanford University, 381 North-South Mall, Stauffer III, Stanford, CA 94305. U.S.A.
Bertrand H LuiDepartment of Bioengineering, Stanford University, The James H. Clark Center, W250, Stanford, CA 94305. U.S.A.
Yuhua HuDepartment of Chemical Engineering, Stanford University, 381 North-South Mall, Stauffer III, Stanford, CA 94305. U.S.A.
Stayce E BeckDMA/OBP/CDER/FDA.
Curtis W FrankDepartment of Chemical Engineering, Stanford University, 381 North-South Mall, Stauffer III, Stanford, CA 94305. U.S.A.
Jennifer R CochranDepartment of Bioengineering, Stanford University, The James H. Clark Center, W250, Stanford, CA 94305. U.S.A ; Department of Bioengineering, Stanford University, The James H. Clark Center, W250, Stanford, CA 94305. U.S.A.
Stanford University · USDelhi Development Authority · IN

Funding

Regenerative Medicine Training Program (RMI)T90DK070103 · NIDDK · STANFORD UNIVERSITY · PI LONGAKER, MICHAEL T · 2004 to 2008
$1.8M
NIDDK NIH HHS T90 DK070103
6 · The paper itself

Abstract

We report a highly tunable quantum dot (QD)-polypeptide hybrid assembly system with potential uses for both molecular imaging and delivery of biomolecular cargo to cancer cells. In this work, we demonstrate the tunability of the assembly system, its application for imaging cancer cells, and its ability to carry a biomolecule. The assemblies are formed through the self-assembly of carboxyl-functionalized QDs and poly(diethylene glycol-L-lysine)-poly(L-lysine) (PEGLL-PLL) diblock copolypeptide molecules, and they are modified with peptide ligands containing a cyclic arginine-glycine-aspartate [c(RGD)] motif that has affinity for α

Indexed as

hybrid materialsnanostructuresquantum dotsself-assemblysupramolecular materials

Identifiers

PMID25750609
PMCPMC4349486
OpenAlexW2059973420

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.