Evidence map›Paper›PMID 25750124›Full record

ReviewAnnals of nuclear medicine2015

The role of molecular imaging in the evaluation of myocardial and peripheral angiogenesis.

Mitchel R Stacy, Jin Chul Paeng, Albert J Sinusas

Open access · hybridAbstract readReview
In one paragraph

Review in Annals of nuclear medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Mitchel R StacyDepartment of Internal Medicine, Section of Cardiovascular Medicine, Yale University School of Medicine, Dana-3, P.O. Box 208017, New Haven, CT, 06520, USA.
Jin Chul Paeng
Albert J Sinusas
Dana (United States) · USSeoul National University Hospital · KRYale University · US

Funding

Training In Multi-modality Molecular & Translational Cardiovascular ImagingT32HL098069 · NHLBI · YALE UNIVERSITY · PI JAMES S DUNCAN, Georges El Fakhri · 2010 to 2026
$5.2M
Non-Invasive Methods for Imaging Myocardial AngiogenesisR01HL065662 · NHLBI · YALE UNIVERSITY · PI SINUSAS, ALBERT J · 2001 to 2009
$3.2M
NHLBI NIH HHS R01 HL065662NHLBI NIH HHS R01 HL65662NHLBI NIH HHS T32 HL098069
6 · The paper itself

Abstract

Angiogenesis, or the formation of new microvasculature, is a physiological process that may occur in the setting of chronic tissue ischemia and can play an important role in improving tissue perfusion and blood flow following myocardial infarction or in the presence of peripheral vascular disease (PVD). Molecular imaging of angiogenesis within the cardiovascular system is a developing field of study. Targeted imaging of angiogenesis has the potential for non-invasive assessment of the underlying molecular signaling events associated with the angiogenic process and, when applied in conjunction with physiological perfusion imaging, may be utilized to predict and evaluate clinical outcomes in the setting of ischemic heart disease or PVD. This review discusses the developing radiotracer-based imaging techniques and technology currently in use that possess potential for clinical translation, with specific focus on PET and SPECT imaging of myocardial and peripheral angiogenesis.

Indexed as

AnimalsExtremitiesHumansIschemiaMolecular ImagingMyocardial IschemiaNeovascularization, PathologicRadiopharmaceuticalsTomography, Emission-ComputedRadiopharmaceuticals

Identifiers

PMID25750124
PMCPMC4661208
OpenAlexW1965832411

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.