ArticleAge (Dordrecht, Netherlands)2015
Mediterranean diet and leukocyte telomere length in a multi-ethnic elderly population.
Article in Age (Dordrecht, Netherlands), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 5 syntheses or guidelines pooled it, 77 citations in OpenAlex.
- The Impact of Foods, Nutrients, or Dietary Patterns on Telomere Length in Childhood and Adolescence: A Systematic Review.Nutrients · 2022Pooled it
- The Effect of Nutrition on Aging-A Systematic Review Focusing on Aging-Related Biomarkers.Nutrients · 2022Pooled it
- Mediterranean Diet and Telomere Length: A Systematic Review and Meta-Analysis.Advances in nutrition (Bethesda, Md.) · 2020Pooled it
- Impact of Nutrition on Telomere Health: Systematic Review of Observational Cohort Studies and Randomized Clinical Trials.Advances in nutrition (Bethesda, Md.) · 2020Pooled it
- Dietary patterns, food groups and telomere length: a systematic review of current studies.European journal of clinical nutrition · 2017Pooled it
- Dietary inflammatory index and telomere length in subjects with a high cardiovascular disease risk from the PREDIMED-NAVARRA study: cross-sectional and longitudinal analyses over 5 y.The American journal of clinical nutrition · 2015Trial
- Longitudinal association of ultra-processed food consumption with biological aging: the mediating role of adiposity measures.GeroScience · 2026Article
- Geroprotective applications of oleuropein and hydroxytyrosol through the hallmarks of ageing.GeroScience · 2026Review
- Role of nut and seed intake on telomere length as a biomarker of ageing: a systematic review of observational and interventional studies.The British journal of nutrition · 2025Review
- Article
- Vitamin D and Colorectal Cancer Prevention: Immunological Mechanisms, Inflammatory Pathways, and Nutritional Implications.Nutrients · 2025Review
- Association of monocyte-lymphocyte ratio with peripheral arterial disease in US participants: a retrospective cross-sectional study.Frontiers in cardiovascular medicine · 2025Article
- Aging Processes Are Affected by Energy Balance: Focused on the Effects of Nutrition and Physical Activity on Telomere Length.Current nutrition reports · 2024Review
- Telomeres and aging: on and off the planet!Biogerontology · 2024Review
- Diet and Aging: The Role of Polyphenol-Rich Diets in Slow Down the Shortening of Telomeres: A Review.Antioxidants (Basel, Switzerland) · 2023Review
- Associations between the New DNA-Methylation-Based Telomere Length Estimator, the Mediterranean Diet and Genetics in a Spanish Population at High Cardiovascular Risk.Antioxidants (Basel, Switzerland) · 2023Article
- Associations between Metabolomic Biomarkers of Avocado Intake and Glycemia in the Multi-Ethnic Study of Atherosclerosis.The Journal of nutrition · 2023Article
- The Possible Role of Food and Diet in the Quality of Life in Patients with COPD-A State-of-the-Art Review.Nutrients · 2023Review
- Influence of the Mediterranean Diet on Healthy Aging.International journal of molecular sciences · 2023Review
- A healthy lifestyle is positively associated with mental health and well-being and core markers in ageing.BMC medicine · 2022Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
Abstract
Leukocyte telomere length (LTL) is considered as the marker of biological aging and may be related to environmental factors. The current study aimed to examine the relation between Mediterranean-type diet and LTL. We used a cross-sectional study of 1743 multi-ethnic community residents of New York aged 65 years or older. Mediterranean-type diet (MeDi) was calculated from dietary information collected using a food frequency questionnaire. LTL was measured from leukocyte DNA using a real-time PCR method to measure T/S ratio, the ratio of telomere (T) to single-copy gene (S) sequence. Regression analysis showed that the MeDi score was not associated with LTL in the overall study population (β = 12.5; p = 0.32) after adjusting for age, sex, education, ethnicity, caloric intake, smoking, and physical and leisure activities. However, we found a significant association between MeDi and LTL among non-Hispanic whites (β = 48.3; p = 0.05), and the results held after excluding dementia subjects (β = 49.6; p = 0.05). We further found that, in the whole population, vegetable and cereal consumption above the sex-specific population median was associated with longer LTL (β = 89.1, p = 0.04) and shorter LTL (β = -93.5; p = 0.03), respectively. Among non-Hispanic whites, intake of meat or dairy below sex-specific population medians was associated with longer LTL (β = 154.7, p = 0.05; β = 240.5, p < 0.001, respectively). We found that higher adherence to a MeDi was associated with longer LTL among whites but not among African Americans and Hispanics. Additionally, a diet high in vegetables but low in cereal, meat, and dairy might be associated with longer LTL among healthy elderly.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.