ArticleBrain imaging and behavior2016
Functional neuroanatomical correlates of episodic memory impairment in early phase psychosis.
Article in Brain imaging and behavior, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Repetitive transcranial magnetic stimulation: advances for psychiatric disorders.Frontiers in psychiatry · 2026Review
- Memory in Psychiatric Disorders: A Review.Life (Basel, Switzerland) · 2025Review
- Hippocampal subfield activity in schizophrenia: Effects of the disease course.Schizophrenia research · 2025Article
- Neural subnetwork signatures distinguishing source and item memory retrieval: A meta-analysis of 66 fMRI studies.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Elucidating gut microbiota-hippocampus interactions in emerging psychosis: A new perspective for the development of early interventions for memory impairments.Frontiers in psychiatry · 2023Article
- A public-private collaboration model for clinical innovation.Clinical and translational science · 2022Review
- No association between cortical dopamine D2 receptor availability and cognition in antipsychotic-naive first-episode psychosis.NPJ schizophrenia · 2021Article
- Repetitive Transcranial Magnetic Stimulation as a Therapeutic and Probe in Schizophrenia: Examining the Role of Neuroimaging and Future Directions.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2021Review
- Functional connectivity abnormalities of the long-axis hippocampal subregions in schizophrenia during episodic memory.NPJ schizophrenia · 2021Article
- Neural Signatures of Memory Encoding in Schizophrenia Are Modulated by Antipsychotic Treatment.Neuropsychobiology · 2021Article
- Hyperactivity and Reduced Activation of Anterior Hippocampus in Early Psychosis.The American journal of psychiatry · 2019Article
- Altered Brain Activation During Memory Retrieval Precedes and Predicts Conversion to Psychosis in Individuals at Clinical High Risk.Schizophrenia bulletin · 2019Article
- Neural activation in response to the two sides of emotion.Neuroscience letters · 2018Article
- Classification of Autism Spectrum Disorder Using Random Support Vector Machine Cluster.Frontiers in genetics · 2018Article
- Episodic memory functions in first episode psychosis and clinical high risk individuals.Schizophrenia research · 2017Article
- Verbal memory impairments in schizophrenia associated with cortical thinning.NeuroImage. Clinical · 2016Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
Studies have demonstrated that episodic memory (EM) is often preferentially disrupted in schizophrenia. The neural substrates that mediate EM impairment in this illness are not fully understood. Several functional magnetic resonance imaging (fMRI) studies have employed EM probe tasks to elucidate the neural underpinnings of impairment, though results have been inconsistent. The majority of EM imaging studies have been conducted in chronic forms of schizophrenia with relatively few studies in early phase patients. Early phase schizophrenia studies are important because they may provide information regarding when EM deficits occur and address potential confounds more frequently observed in chronic populations. In this study, we assessed brain activation during the performance of visual scene encoding and recognition fMRI tasks in patients with earlyphase psychosis (n = 35) and age, sex, and race matched healthy control subjects (n = 20). Patients demonstrated significantly lower activation than controls in the right hippocampus and left fusiform gyrus during scene encoding and lower activation in the posterior cingulate, precuneus, and left middle temporal cortex during recognition of target scenes. Symptom levels were not related to the imaging findings, though better cognitive performance in patients was associated with greater right hippocampal activation during encoding. These results provide evidence of altered function in neuroanatomical circuitry subserving EM early in the course of psychotic illness, which may have implications for pathophysiological models of this illness.
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