Evidence map›Paper›PMID 25749850›Full record

ArticleJournal of materials science. Materials in medicine2015

In vivo study of novelly formulated porcine-derived fibrinogen as an efficient sealant.

Zhang Liu, Lidong Guan, Kang Sun, Xujun Wu, Ling Su, Jifeng Hou, Miao Ye, Weihong Huang, Hongbing He

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of materials science. Materials in medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Zhang LiuSchool of Materials Science and Engineering, Shanghai JiaoTong University, Shanghai, China.
Lidong Guan
Kang Sun
Xujun Wu
Ling Su
Jifeng Hou
Miao Ye
Weihong Huang
Hongbing He
Shanghai Jiao Tong University · CNNational Institutes for Food and Drug Control · CNFudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fibrinogen has been used as surgical sealant in the clinical setting for decades. The application of human plasma-derived fibrinogen is limited due to high cost and the risk of prion and virus infection. We developed a novel arginine-formulated fibrinogen from cryoprecipitates of porcine plasma. This porcine-derived fibrinogen exhibited excellent stability during sterilization and better hemostatic efficacy than a leading commercial hemostatic product in a nonlethal hemorrhage model. Therefore, it has the potential to be more economical and readily available while having a decreased risk of human blood-borne pathogen transmission.

Indexed as

Tissue AdhesivesAnimalsCircular DichroismElectrophoresis, Polyacrylamide GelFemaleFibrinogenMaleRabbitsSwineFibrinogenTissue Adhesives

Identifiers

PMID25749850
OpenAlexW2016469809

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.