Evidence map›Paper›PMID 25749813›Full record

ArticleEuropean radiology2015

Use of Model-Based Iterative Reconstruction (MBIR) in reduced-dose CT for routine follow-up of patients with malignant lymphoma: dose savings, image quality and phantom study.

Edouard Hérin, François Gardavaud, Mélanie Chiaradia, Pauline Beaussart, Philippe Richard, Madeleine Cavet, Jean-François Deux, Corinne Haioun, Emmanuel Itti, Alain Rahmouni and 1 more

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Article in European radiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

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20citing papers in PubMed
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20 citing papers in PubMed.

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  8. Impact of CT reconstruction algorithm on auto-segmentation performance.Journal of applied clinical medical physics · 2019
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5 · Who and what money

Authors and funding

11 authors.

Edouard HérinAP-HP, Hôpitaux Universitaires Henri Mondor, Imagerie Médicale, Créteil, 94010, France.
François Gardavaud
Mélanie Chiaradia
Pauline Beaussart
Philippe Richard
Madeleine Cavet
Jean-François Deux
Corinne Haioun
Emmanuel Itti
Alain Rahmouni
Alain Luciani

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate both in vivo and in phantom studies, dose reduction, and image quality of body CT reconstructed with model-based iterative reconstruction (MBIR), performed during patient follow-ups for lymphoma.

methodsThis study included 40 patients (mean age 49 years) with lymphoma. All underwent reduced-dose CT during follow-up, reconstructed using MBIR or 50 % advanced statistical iterative reconstruction (ASIR). All had previously undergone a standard dose CT with filtered back projection (FBP) reconstruction. The volume CT dose index (CTDIvol), the density measures in liver, spleen, fat, air, and muscle, and the image quality (noise and signal to noise ratio, SNR) (ANOVA) observed using standard or reduced-dose CT were compared both in patients and a phantom study (Catphan 600) (Kruskal Wallis).

resultsThe CTDIvol was decreased on reduced-dose body CT (4.06 mGy vs. 15.64 mGy p < 0.0001). SNR was higher in reduced-dose CT reconstructed with MBIR than in 50 % ASIR or than standard dose CT with FBP (patients, p ≤ 0.01; phantoms, p = 0.003). Low contrast detectability and spatial resolution in phantoms were not altered on MBIR-reconstructed CT (p ≥ 0.11).

conclusionReduced-dose CT with MBIR reconstruction can decrease radiation dose delivered to patients with lymphoma, while keeping an image quality similar to that obtained on standard-dose CT. KEY POINTS: • In lymphoma patients, CT dose reduction is a major concern. • Reduced-dose body CT provides a fourfold radiation dose reduction. • Optimized CT reconstruction techniques (MBIR) can maintain image quality.

Indexed as

Phantoms, ImagingRadiation DosageAdultAgedAged, 80 and overAlgorithmsFemaleFollow-Up StudiesHumansImage Processing, Computer-AssistedLymphomaMaleMiddle AgedRadiographic Image Interpretation, Computer-AssistedSignal-To-Noise RatioTomography, X-Ray Computed

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.