ArticleEuropean radiology2015
Investigation of Apparent Diffusion Coefficient from Ultra-high b-Values in Parkinson's Disease.
Article in European radiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 38 citations in OpenAlex.
- Ultra-high b-value DWI accurately identifies isocitrate dehydrogenase genotypes and tumor subtypes of adult-type diffuse gliomas.European radiology · 2024Article
- Alterations of apparent diffusion coefficient from ultra high b-values in the bilateral thalamus and striatum in MRI-negative drug-resistant epilepsy.Epilepsia open · 2024Article
- Ultra-high b-Value DWI in predicting progression risk of locally advanced rectal cancer: a comparative study with routine DWI.Cancer imaging : the official publication of the International Cancer Imaging Society · 2023Article
- A three-component multi-b-value diffusion-weighted imaging might be a useful biomarker for detecting microstructural features in gliomas with differences in malignancy and IDH-1 mutation status.European radiology · 2023Article
- Multi-parameter diffusion and perfusion magnetic resonance imaging and radiomics nomogram for preoperative evaluation of aquaporin-1 expression in rectal cancer.Abdominal radiology (New York) · 2022Article
- Ultra-high b value DWI in distinguishing fresh gray matter ischemic lesions from white matter ones: a comparative study with routine and high b value DWI.Quantitative imaging in medicine and surgery · 2021Article
- Study of Diffusion Weighted Imaging Derived Diffusion Parameters as Biomarkers for the Microenvironment in Gliomas.Frontiers in oncology · 2021Article
- Glymphatic Dysfunction: A Bridge Between Sleep Disturbance and Mood Disorders.Frontiers in psychiatry · 2021Article
- Associations Between Diffusion Dynamics and Functional Outcome in Acute and Early Subacute Ischemic Stroke.Clinical neuroradiology · 2020Article
- Based on Histogram Analysis: ADCScientific reports · 2020Article
- Observational
- Characterization of Alzheimer's Disease Using Ultra-high b-values Apparent Diffusion Coefficient and Diffusion Kurtosis Imaging.Aging and disease · 2019Article
- The value of multi ultra high-b-value DWI in grading cerebral astrocytomas and its association with aquaporin-4.The British journal of radiology · 2018Article
- A Modified Tri-Exponential Model for Multi-Frontiers in neuroscience · 2018Article
- Microstructural Abnormalities of Basal Ganglia and Thalamus in Bipolar and Unipolar Disorders: A Diffusion Kurtosis and Perfusion Imaging Study.Psychiatry investigation · 2017Article
- Comparison between ultra-high and conventional mono b-value DWI for preoperative glioma grading.Oncotarget · 2017Article
- Investigation of aquaporins and apparent diffusion coefficient from ultra-high b-values in a rat model of diabetic nephropathy.European radiology experimental · 2017Article
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo assess brain damage in Parkinson's disease (PD) based on apparent diffusion coefficient (ADC) data obtained from ultra-high b-values.
methodsEighteen PD patients and 18 controls received diffusion-weighted imaging (DWI) with standard b-values (0, 1,000 s/mm(2)) and 15 b-values (0-5,000 s/mm(2)). Standard ADC (ADCst) maps were calculated from standard b-values, while maps of pure diffusion coefficients (D), pseudo-diffusion coefficients (D(*)), and ultra-high ADCs (ADCuh) were calculated from the 15 b-values using a tri-component model. In this model, D and D(*) values were quantified with a bi-exponential equation using b-values less than 2,000 s/mm(2), while ADCuh was quantified by fitting the signals at ultra-high b-values (2,000-5,000 s/mm(2)) to the mono-exponential equation. ADCst, ADCuh, D, and D(*) of the globus pallidus (GP), putamen (P), and substantia nigra (SN) were compared between PD patients and normal control subjects.
resultsADCuh of the GP, P, and SN was significantly lower in PD patients than those in control subjects (P < 0.001), while ADCst, D, and D(*) of the GP, P and SN were not different between the two groups (P > 0.05).
conclusionsADCuh may be a useful measurement for evaluating brain damage in PD patients. KEY POINTS: • DWI with ultra-high b-values may provide new insight into Parkinson's disease pathology • ADC calculated using ultra-high b-values is different between PD and controls • ADC uh may be associated with water transportation by aquaporins.
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