Evidence map›Paper›PMID 25749768›Full record

ReviewAllergy, asthma & immunology research2015

Seven steps to the diagnosis of NSAIDs hypersensitivity: how to apply a new classification in real practice?

Marek L Kowalski, Joanna S Makowska

Open access · hybridAbstract readReview
In one paragraph

Review in Allergy, asthma & immunology research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
9.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it, 103 citations in OpenAlex.

  1. Non-steroidal anti-inflammatory drugs for sciatica.The Cochrane database of systematic reviews · 2016
    Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Review
  7. Losartan-induced Angioedema: A Case Report and Review of Literature.Journal of community hospital internal medicine perspectives · 2026
    Article
  8. Article
  9. Review
  10. Article
  11. Observational
  12. Article
  13. An Update on Nonsteroidal Anti-Inflammatory Drug-Induced Urticaria.Endocrine, metabolic & immune disorders drug targets · 2024
    Review
  14. Why Pharmacovigilance of Non-steroidal Anti-inflammatory Drugs is Important in India?Endocrine, metabolic & immune disorders drug targets · 2024
    Review
  15. Anti-Inflammatory Activity ofPharmaceuticals (Basel, Switzerland) · 2023
    Article
  16. Article
  17. Aspirin-exacerbated respiratory disease: Updates in the era of biologics.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2023
    Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Marek L KowalskiDepartment of Immunology, Rheumatology and Allergy, Medical University of Lodz, Lodz, Poland. marek.kowalski@csk.umed.lodz.pl.
Joanna S MakowskaDepartment of Immunology, Rheumatology and Allergy, Medical University of Lodz, Lodz, Poland.
Medical University of Lodz · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Frequent use of non-steroidal anti-inflammatory drugs (NSAIDs) has been paralleled by increasing occurrence of adverse reactions, which vary from mild local skin rashes or gastric irritation to severe, generalized symptoms and even life-threatening anaphylaxis. NSAID-induced hypersensitivity reactions may involve both immunological and non-immunological mechanisms and should be differentiated from type A adverse reactions. Clinical diagnosis and effective management of a hypersensitive patient cannot be achieved without identifying the underlying mechanism. In this review, we discuss the current classification of NSAID-induced adverse reactions and propose a practical diagnostic algorithm that involves 7 steps leading to the determination of the type of NSAID-induced hypersensitivity and allows for proper patient management.

Indexed as

aspirinaspirin hypersensitivitydrug allergyNonsteroidal anti-inflammatory drugsNSAID-induced hypersensitivity

Identifiers

PMID25749768
PMCPMC4446629
OpenAlexW2018500139

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.