SynthesisDrugs & aging2015
The burden of non-adherence to cardiovascular medications among the aging population in Australia: a meta-analysis.
Synthesis in Drugs & aging, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 32 citations in OpenAlex.
- Trial
- Enhancing Therapy Adherence: Impact on Clinical Outcomes, Healthcare Costs, and Patient Quality of Life.Medicina (Kaunas, Lithuania) · 2025Review
- Article
- Level of medication adherence and its determinants of cardiovascular disease patients attending at specialized teaching hospitals of Amhara regional state, Ethiopia: a multicenter cross-sectional study.Frontiers in pharmacology · 2024Article
- Estimating medication adherence from Electronic Health Records: comparing methods for mining and processing asthma treatment prescriptions.BMC medical research methodology · 2023Article
- Smart About Meds (SAM): a pilot randomized controlled trial of a mobile application to improve medication adherence following hospital discharge.JAMIA open · 2021Article
- Linkage of primary care prescribing records and pharmacy dispensing Records in the Salford Lung Study: application in asthma.BMC medical research methodology · 2020Article
- Reducing Stroke Risk in Atrial Fibrillation: Adherence to Guidelines Has Improved, but Patient Persistence with Anticoagulant Therapy Remains Suboptimal.Korean circulation journal · 2019Review
- Adherence to cardiovascular medication: a review of systematic reviews.Journal of public health (Oxford, England) · 2019Review
- Prevention of stroke: a strategic global imperative.Nature reviews. Neurology · 2016Review
- Factors Influencing Non-Persistence with Antiplatelet Medications in Elderly Patients After Ischaemic Stroke.Drugs & aging · 2016Article
- A renewed Medication Adherence Alliance call to action: harnessing momentum to address medication nonadherence in the United States.Patient preference and adherence · 2016Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNon-adherence to cardiovascular medications is a problem worldwide, even in Australia, which has a socialized medical system, Medicare.
objectiveThe aim of this systematic review was to evaluate the burden of non-adherence to cardiovascular medications and factors thereof in Australia. DATA SOURCES: Pubmed, Embase, CINAHL, PsycInfo, Cochrane Library databases were searched. ELIGIBILITY CRITERIA: Articles were included if they were in English, peer-reviewed and provided empirical data on adherence to cardiovascular medication for an Australian cohort.
methodsA meta-analysis of prevalence of medication non-adherence using the double arcsine square root transformed proportion was undertaken. Studies were pooled in homogenous prevalence groups and factors that differed across groups were ascertained.
resultsFive studies, including eight datasets and 76,867 subjects were analyzed. Three more or less homogenous prevalence categories were discernable: low [19 %, 95 % confidence interval (CI) 15-24], moderate (26 %, 95 % CI 23-29) and high (43 %, 95 % CI 43-44; this was a single study) prevalence of non-adherence. There were minimal clear patterns across groups in relation to typical factors of non-adherence (patient, condition, healthcare system or socioeconomic factors). Measurements used for non-adherence were similar for six of the eight included datasets, suggesting this did not affect prevalence of non-adherence or inclusion in a prevalence group.
conclusionsNon-adherence to cardiovascular medications is a serious problem in the aging Australian setting with an overall prevalence of between 14 and 43 %. The lack of patterns in the typical factors of non-adherence suggests that another factor, such as patients' beliefs about their conditions and medications, may be playing a stronger role in their non-adherence than clinical or sociodemographic factors. This is an area for further research.
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