Trial reportJournal of the National Cancer Institute. Monographs2014
A hybrid effectiveness-implementation trial of an evidence-based exercise intervention for breast cancer survivors.
Trial report in Journal of the National Cancer Institute. Monographs, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 3 syntheses or guidelines pooled it, 69 citations in OpenAlex.
- Barriers and Facilitators to the Adoption of Evidence-Based Interventions for Adults Within Occupational and Physical Therapy Practice Settings: A Systematic Review.Archives of physical medicine and rehabilitation · 2023Pooled it
- Exercise interventions for people diagnosed with cancer: a systematic review of implementation outcomes.BMC cancer · 2021Pooled it
- The Independent Effects of Strength Training in Cancer Survivors: a Systematic Review.Current oncology reports · 2016Pooled it
- Planning and evaluating an integrated clinical exercise oncology service: an exploratory mixed-methods study.BMC health services research · 2024Trial
- Feasibility of Implementing Physical Activity Behavior Change Counseling in an Existing Cancer-Exercise Program.International journal of environmental research and public health · 2021Trial
- The women in steady exercise research (WISER) survivor trial: The innovative transdisciplinary design of a randomized controlled trial of exercise and weight-loss interventions among breast cancer survivors with lymphedema.Contemporary clinical trials · 2017Trial
- Weight Lifting and Physical Function Among Survivors of Breast Cancer: A Post Hoc Analysis of a Randomized Controlled Trial.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2015Trial
- An exploratory analysis of 24-h movement behaviors in individuals with cancer completing a 12-week resistance exercise intervention.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Facilitators to the implementation of exercise into cancer care: a systematic review.Journal of cancer survivorship : research and practice · 2026Review
- Multidisciplinary perspectives in exercise oncology across the translational research continuum.Journal of the National Cancer Institute. Monographs · 2025Review
- Feasibility, safety, and adherence of home-based exercise interventions in people diagnosed with cancer: a systematic review.Journal of cancer survivorship : research and practice · 2025Review
- Protocol for a hybrid II study exploring the feasibility of delivering, evaluating, and implementing a self-management programme for people with neuromuscular diseases at a specialist neuromuscular centre.Pilot and feasibility studies · 2023Article
- Implementation barriers to integrating exercise as medicine in oncology: an ecological scoping review.Journal of cancer survivorship : research and practice · 2022Article
- Promoting Physical Activity in Rural Settings: Effectiveness and Potential Strategies.Translational journal of the American College of Sports Medicine · 2021Article
- The challenge of timing: a qualitative study on clinician and patient perspectives about implementing exercise-based rehabilitation in an acute cancer treatment setting.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020Article
- We have the program, what now? Development of an implementation plan to bridge the research-practice gap prevalent in exercise oncology.The international journal of behavioral nutrition and physical activity · 2020Article
- The impact of arm lymphedema on healthcare utilization during long-term breast cancer survivorship: a population-based cohort study.Journal of cancer survivorship : research and practice · 2020Article
- Implementing Exercise in Healthcare Settings: The Potential of Implementation Science.Sports medicine (Auckland, N.Z.) · 2020Article
- Implementing Strength after Breast Cancer (SABC) in outpatient rehabilitation clinics: mapping clinician survey data onto key implementation outcomes.Implementation science communications · 2020Article
- Dissemination and implementation research in sports and exercise medicine and sports physical therapy: translating evidence to practice and policy.BMJ open sport & exercise medicine · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundThe primary aims of this hybrid Type 1 effectiveness-implementation trial were to quantitatively assess whether an evidence-based exercise intervention for breast cancer survivors, Strength After Breast Cancer, was safe and effective in a new setting and to qualitatively assess barriers to implementation.
methodsA cohort of 84 survivors completed measurements related to limb volume, muscle strength, and body image at baseline, 67 survivors completed measurements 12 months later. Qualitative methods were used to understand barriers to implementation experienced by referring oncology clinicians and physical therapists who delivered the program.
resultsSimilar to the efficacy trial, the revised intervention demonstrated safety with regard to lymphedema, and led to improvements in lymphedema symptoms, muscular strength, and body image. Comparison of effects in the effectiveness trial to effects in the efficacy trial revealed larger strength increases in the efficacy trial than in the effectiveness trial (P < .04), but few other differences were found. Qualitative implementation data suggested significant barriers around intervention characteristics, payment, eligibility criteria, the referral process, the need for champions (ie, advocates), and the need to adapt during implementation of the intervention, which should be considered in future dissemination and implementation efforts.
conclusionsThis trial successfully demonstrated that a physical therapy led strength training program for breast cancer survivors can be implemented in a community setting while retaining the effectiveness and safety of the clinical trial. However, during the translation process, strategies to reduce barriers to implementation are required. This new program can inform larger scale dissemination and implementation efforts.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.