ReviewSurvey of ophthalmology
Role of dendritic cell subsets in immunity and their contribution to noninfectious uveitis.
Review in Survey of ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed.
- Development and preclinical characterization of AMG 329: a human antibody neutralizing FLT3 ligand.mAbs · 2025Article
- A Comprehensive Review on Porcine Reproductive and Respiratory Syndrome Virus with Emphasis on Immunity.Vaccines · 2024Review
- Overview of dendritic cells and related pathways in autoimmune uveitis.Open life sciences · 2024Review
- Article
- Ginsenoside Rg5 promotes wound healing in diabetes by reducing the negative regulation of SLC7A11 on the efferocytosis of dendritic cells.Journal of ginseng research · 2023Article
- Human immunocompetent choroid-on-chip: a novel tool for studying ocular effects of biological drugs.Communications biology · 2022Article
- Immune System Alterations in Multiple Myeloma: Molecular Mechanisms and Therapeutic Strategies to Reverse Immunosuppression.Cancers · 2021Review
- CD47 Deficiency Ameliorates Ocular Autoimmune Inflammation.Frontiers in immunology · 2021Article
- Regulation of the Migration of Distinct Dendritic Cell Subsets.Frontiers in cell and developmental biology · 2021Review
- The Cellular Composition of the Uveal Immune Environment.Frontiers in medicine · 2021Review
- Myeloid and Plasmacytoid Dendritic Cells and Cancer - New Insights.Open access Macedonian journal of medical sciences · 2019Review
- Retinal microglia initiate neuroinflammation in ocular autoimmunity.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- CD83Journal of cellular and molecular medicine · 2019Article
- Soluble CD83 Alleviates Experimental Autoimmune Uveitis by Inhibiting Filamentous Actin-Dependent Calcium Release in Dendritic Cells.Frontiers in immunology · 2018Article
- Elevated CD1c+ Myeloid Dendritic Cell Proportions Associate With Clinical Activity and Predict Disease Reactivation in Noninfectious Uveitis.Investigative ophthalmology & visual science · 2016Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Dendritic cells (DCs) are a heterogeneous population. Murine DCs consist of conventional DCs (cDCs) and plasmacytoid DCs (pDCs). In humans, the analogous populations are myeloid DCs (mDCs) and pDCs. Though distinct in phenotypes and functions, studies have shown that these DC subsets may interact or "crosstalk" during immune responses. For example, cDCs may facilitate pDC maturation, and pDCs may enhance antigen presentation of cDCs in certain pathogenic conditions or even take on a cDC phenotype themselves. The role of DCs in noninfectious uveitis has been studied primarily in the experimental autoimmune uveitis mouse model and to a more limited extent in patients. Recent evidence shows that the number, phenotype, and function of DC subsets are altered in this disease. We provide an overview of selected recent developments of pDCs and cDCs/mDCs, with special attention to their interaction and the dual roles of DC subsets in noninfectious uveitis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.