Evidence map›Paper›PMID 25749094›Full record

ReviewBrain research2015

Cellular connections, microenvironment and brain angiogenesis in diabetes: Lost communication signals in the post-stroke period.

Adviye Ergul, John Paul Valenzuela, Abdelrahman Y Fouda, Susan C Fagan

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Brain research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Adviye ErgulCharlie Norwood Veterans Affairs Medical Center, Augusta, GA 30904, USA; Department of Physiology, Medical College of Georgia, Georgia Regents University, 1120 15th Street, CA 2094, Augusta, GA 30912, USA; Program in Clinical and Experimental Therapeutics, College of Pharmacy, University of Georgia, Augusta, GA 30912, USA. Electronic address: aergul@gru.edu.
John Paul ValenzuelaDepartment of Physiology, Medical College of Georgia, Georgia Regents University, 1120 15th Street, CA 2094, Augusta, GA 30912, USA.
Abdelrahman Y FoudaCharlie Norwood Veterans Affairs Medical Center, Augusta, GA 30904, USA; Program in Clinical and Experimental Therapeutics, College of Pharmacy, University of Georgia, Augusta, GA 30912, USA.
Susan C FaganCharlie Norwood Veterans Affairs Medical Center, Augusta, GA 30904, USA; Department of Neurology, Medical College of Georgia, Georgia Regents University, Augusta, GA 30912, USA; Program in Clinical and Experimental Therapeutics, College of Pharmacy, University of Georgia, Augusta, GA 30912, USA.
Augusta University · USAugusta University Health · USCharlie Norwood VA Medical Center · US

Funding

Vascular Injury and Recovery in Diabetic Ischemic StrokeRF1NS083559 · NINDS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI ERGUL, ADVIYE · 2020 to 2022
$2.4M
Vascular Injury and Recovery in Diabetic Ischemic StrokeR01NS083559 · NINDS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI ERGUL, ADVIYE · 2014 to 2018
$1.9M
Mechanisms of Vascular Protection after Acute StrokeR01NS063965 · NINDS · UNIVERSITY OF GEORGIA · PI FAGAN, SUSAN C · 2009 to 2013
$1.4M
Cerebral Arteriole Structure/Function in Diabetic Ischemic Brain InjuryI01BX000347 · VA · RALPH H JOHNSON VA MEDICAL CENTER · PI ERGUL, ADVIYE · 2009 to 2025
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Mechanisms and Consequences of Hypertension after StrokeI01BX000891 · VA · CHARLIE NORWOOD VA MEDICAL CENTER · PI FAGAN, SUSAN C · 2011 to 2014
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BLRD VA I01 BX000347BLRD VA I01 BX000891Intramural VA VA999999NINDS NIH HHS NS063965NINDS NIH HHS NS083559NINDS NIH HHS NS083559S1NINDS NIH HHS NS083559S2NINDS NIH HHS R01 NS063965NINDS NIH HHS R01 NS083559NINDS NIH HHS RF1 NS083559
6 · The paper itself

Abstract

Diabetes not only increases the risk but also worsens the motor and cognitive recovery after stroke, which is the leading cause of disability worldwide. Repair after stroke requires coordinated communication among various cell types in the central nervous system as well as circulating cells. Vascular restoration is critical for the enhancement of neurogenesis and neuroplasticity. Given that vascular disease is a major component of all complications associated with diabetes including stroke, this review will focus on cellular communications that are important for vascular restoration in the context of diabetes. This article is part of a Special Issue entitled SI: Cell Interactions In Stroke.

Indexed as

AnimalsBrainCell CommunicationDiabetes MellitusHumansNeovascularization, PathologicStrokeAngiogenesisDiabetesStrokeVascular restoration

Identifiers

PMID25749094
PMCPMC4743654
OpenAlexW2059306066

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.