Evidence map›Paper›PMID 25748648›Full record

ArticleGut2015

Global patterns of cardia and non-cardia gastric cancer incidence in 2012.

A Colquhoun, M Arnold, J Ferlay, K J Goodman, D Forman, I Soerjomataram

Abstract read
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In one paragraph

Article in Gut, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 201 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
201citing papers in PubMed, 10 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

201 citing papers in PubMed, 10 syntheses or guidelines pooled it.

  1. Pooled it
  2. Dose-response association between cigarette smoking and gastric cancer risk: a systematic review and meta-analysis.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2024
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  18. The descriptive epidemiology of gastric cancer in Afghanistan: a population-based cancer registry, 2018-2020.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2026
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141 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

A ColquhounSchool of Public Health, University of Alberta, Edmonton, Alberta, Canada.
M ArnoldSection of Cancer Surveillance, International Agency for Research on Cancer, Lyon, France.
J FerlaySection of Cancer Surveillance, International Agency for Research on Cancer, Lyon, France.
K J GoodmanSchool of Public Health, University of Alberta, Edmonton, Alberta, Canada.
D FormanSection of Cancer Surveillance, International Agency for Research on Cancer, Lyon, France.
I SoerjomataramSection of Cancer Surveillance, International Agency for Research on Cancer, Lyon, France.

Funding

World Health Organization 001
6 · The paper itself

Abstract

objectiveGlobally, gastric cancer incidence shows remarkable international variation and demonstrates distinct characteristics by the two major topographical subsites, cardia (CGC) and non-cardia (NCGC). Because global incidence estimates by subsite are lacking, we aimed to describe the worldwide incidence patterns of CGC and NCGC separately.

designUsing Cancer Incidence in Five Continents Volume X (CI5X), we ascertained the proportions of CGC and NCGC by country, sex and age group (<65 and ≥65 years). These derived proportions were applied to GLOBOCAN 2012 data to estimate country-specific age-standardised CGC and NCGC incidence rates (ASR). Regional proportions were used to estimate rates for countries not included in CI5X.

resultsAccording to our estimates, in 2012, there were 260,000 cases of CGC (ASR 3.3 per 100,000) and 691,000 cases of NCGC (ASR 8.8) worldwide. The highest regional rates of both gastric cancer subsites were in Eastern/Southeastern Asia (in men, ASRs: 8.7 and 21.7 for CGC and NCGC, respectively). In most countries NCGC occurred more frequently than CGC with an average ratio of 2:1; however, in some populations where NCGC incidence rates were lower than the global average, CGC rates were similar or higher than NCGC rates. Men had higher rates than women for both subsites but particularly for CGC (male-to-female ratio 3:1).

conclusionsThis study has, for the first time, quantified global incidence patterns of CGC and NCGC providing new insights into the global burden of these cancers. Country-specific estimates are provided; however, these should be interpreted with caution. This work will support future investigations across populations.

Indexed as

CardiaAfrica, NorthernAfrica South of the SaharaAsiaCaribbean RegionCentral AmericaEuropeFemaleGlobal HealthHumansIncidenceMaleNorth AmericaOceaniaSex FactorsSouth AmericaCANCERCANCER EPIDEMIOLOGYGASTRIC CANCER

Identifiers

PMID25748648

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.