ReviewProceedings of the Japan Academy. Series B, Physical and biological sciences2015
Gene regulatory systems that control gene expression in the Ciona embryo.
Review in Proceedings of the Japan Academy. Series B, Physical and biological sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
15 citing papers in PubMed, 2 citations in OpenAlex.
- A simple inland culture system provides insights into ascidian post-embryonic developmental physiology.Open biology · 2025Article
- Cellular remodeling and JAK inhibition promote zygotic gene expression in the Ciona germline.EMBO reports · 2024Article
- Heterogeneity in maternal mRNAs within clutches of eggs in response to thermal stress during the embryonic stage.BMC ecology and evolution · 2024Article
- Short-Term Exposure to Nanoplastics Does Not Affect Bisphenol A Embryotoxicity to Marine AscidianBiomolecules · 2022Article
- NETISCE: a network-based tool for cell fate reprogramming.NPJ systems biology and applications · 2022Article
- A mosaic of conserved and novel modes of gene expression and morphogenesis in mesoderm and muscle formation of a larval bivalve.Organisms, diversity & evolution · 2022Article
- HES and Mox genes are expressed during early mesoderm formation in a mollusk with putative ancestral features.Scientific reports · 2021Article
- The gene regulatory system for specifying germ layers in early embryos of the simple chordate.Science advances · 2021Article
- Using linkage logic theory to control dynamics of a gene regulatory network of a chordate embryo.Scientific reports · 2021Article
- Article
- Review
- Efficient genome editing using CRISPR-Cas-mediated homology directed repair in the ascidian Ciona robusta.Genesis (New York, N.Y. : 2000) · 2018Article
- Controlling Cell Fate Specification System by Key Genes Determined from Network Structure.iScience · 2018Article
- Diversification of spatiotemporal expression and copy number variation of the echinoid hbox12/pmar1/micro1 multigene family.PloS one · 2017Article
- A Maternal System Initiating the Zygotic Developmental Program through Combinatorial Repression in the Ascidian Embryo.PLoS genetics · 2016Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Transcriptional control of gene expression is one of the most important regulatory systems in animal development. Specific gene expression is basically determined by combinatorial regulation mediated by multiple sequence-specific transcription factors. The decoding of animal genomes has provided an opportunity for us to systematically examine gene regulatory networks consisting of successive layers of control of gene expression. It remains to be determined to what extent combinatorial regulation encoded in gene regulatory networks can explain spatial and temporal gene-expression patterns. The ascidian Ciona intestinalis is one of the animals in which the gene regulatory network has been most extensively studied. In this species, most specific gene expression patterns in the embryo can be explained by combinations of upstream regulatory genes encoding transcription factors and signaling molecules. Systematic scrutiny of gene expression patterns and regulatory interactions at the cellular resolution have revealed incomplete parts of the network elucidated so far, and have identified novel regulatory genes and novel regulatory mechanisms.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.