Evidence map›Paper›PMID 25748478›Full record

Trial reportPloS one2015

Live birth and cumulative live birth rates in expected poor ovarian responders defined by the Bologna criteria following IVF/ICSI treatment.

Joyce Chai, Vivian Chi-Yan Lee, Tracy Wing-Yee Yeung, Hang Wun Raymond Li, Raymond Wun-Hang Li, Pak-Chung Ho, Ernest Hung-Yu Ng

Erratum issuedOpen access · goldAbstract readClinical Trial
In one paragraph

Trial report in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
4.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Joyce ChaiDepartment of Obstetrics and Gynaecology, University of Hong Kong, Hong Kong Special Administrative Region, China.
Vivian Chi-Yan LeeDepartment of Obstetrics and Gynaecology, University of Hong Kong, Hong Kong Special Administrative Region, China.
Tracy Wing-Yee YeungDepartment of Obstetrics and Gynaecology, University of Hong Kong, Hong Kong Special Administrative Region, China.
Hang Wun Raymond Li
Raymond Wun-Hang LiDepartment of Obstetrics and Gynaecology, University of Hong Kong, Hong Kong Special Administrative Region, China.
Pak-Chung HoDepartment of Obstetrics and Gynaecology, University of Hong Kong, Hong Kong Special Administrative Region, China.
Ernest Hung-Yu NgDepartment of Obstetrics and Gynaecology, University of Hong Kong, Hong Kong Special Administrative Region, China.
University of Hong Kong · HK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine the live birth and cumulative live birth rates of expected poor ovarian responders according to the Bologna criteria and to compare their outcomes with those of expected normal responders.

designRetrospective analysis.

settingUniversity infertility clinic. PATIENTS: A total of 1,152 subfertile women undergoing their first in vitro fertilization (IVF) cycle.

interventionsWomen were classified into 4 groups according to the Bologna criteria for comparison. MAIN OUTCOME MEASURE(S): Live birth and cumulative live birth rates.

resultsWomen with expected poor response (POR) had the lowest live birth rate than the other 3 groups (23.8%, p = 0.031). Cumulative live birth rates were significantly lower in those with expected POR than those with expected normal ovarian response (NOR) (35.8% vs 62.8%, p<0.0001). In the subgroup analysis, the cumulative live birth rates in expected PORs were significantly lower in those who had ≤3 oocytes retrieved (18.6% for ≤3 oocytes vs 44.0% for >3 oocytes, p = 0.006) whereas the live birth rates in fresh cycle did not differ (17.8% vs 30.9%, p = 0.108).

conclusionWomen who were expected POR according to the Bologna criteria had lower live birth and cumulative live birth than expected NOR but they still can achieve reasonable treatment outcomes and IVF treatment should not be precluded.

Indexed as

Birth RateFertilization in VitroLive BirthAdultFemaleHong KongHumansPregnancy

Identifiers

PMID25748478
PMCPMC4351960
OpenAlexW2032766179

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.