ArticleEnvironmental health perspectives2015
Occupational Exposure to Benzene and Non-Hodgkin Lymphoma in a Population-Based Cohort: The Shanghai Women's Health Study.
Article in Environmental health perspectives, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.
- Benzene exposure and non-Hodgkin lymphoma: a systematic review and meta-analysis of human studies.The Lancet. Planetary health · 2021Pooled it
- Long-term exposure to low-level ambient BTEX and site-specific cancer risk: A national cohort study in the UK Biobank.Eco-Environment & Health · 2025Article
- Assessment of a Systematic Screening of Occupational Exposures in Malignant Hemopathies in the Rhone-Alpes Area: Prolymphome Study.La Medicina del lavoro · 2025Article
- Occupational Benzene Exposure and Cancer Risk among Chinese Men: A Report from the Shanghai Men's Health Study.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2024Article
- Occupational exposure to benzene and mortality risk of lymphohaematopoietic cancers in the Swiss National Cohort.Scandinavian journal of work, environment & health · 2024Article
- Article
- Review
- Etiology of non-Hodgkin lymphoma: A review from epidemiologic studies.Journal of the National Cancer Center · 2022Review
- Concordance of Occupational Exposure Assessment between the Canadian Job-Exposure Matrix (CANJEM) and Expert Assessment of Jobs Held by Women.Annals of work exposures and health · 2022Article
- Benzene exposure increases the risk of non-Hodgkin's lymphoma: a systematic review and meta-analysis of observational studies.Translational cancer research · 2022Article
- Research development and trends of benzene-induced leukemia from 1990 to 2019-A bibliometric analysis.Environmental science and pollution research international · 2022Review
- Influence of Rurality, Race, and Ethnicity on Non-Hodgkin Lymphoma Incidence.Clinical lymphoma, myeloma & leukemia · 2020Article
- Benzene exposure-response and risk of lymphoid neoplasms in Chinese workers: A multicenter case-cohort study.American journal of industrial medicine · 2020Article
- The disease burden attributable to 18 occupational risks in China: an analysis for the global burden of disease study 2017.Environmental health : a global access science source · 2020Article
- Estimation of Source-Specific Occupational Benzene Exposure in a Population-Based Case-Control Study of Non-Hodgkin Lymphoma.Annals of work exposures and health · 2019Review
- Evaluating Exposure-Response Associations for Non-Hodgkin Lymphoma with Varying Methods of Assigning Cumulative Benzene Exposure in the Shanghai Women's Health Study.Annals of work exposures and health · 2017Article
- CONSTANCES: a general prospective population-based cohort for occupational and environmental epidemiology: cohort profile.Occupational and environmental medicine · 2017Article
Corrections and comments
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Authors and funding
18 authors at 8 institutions in 3 countries.
Funding
Abstract
backgroundThe association between benzene exposure and non-Hodgkin lymphoma (NHL) has been the subject of debate as a result of inconsistent epidemiologic evidence. An International Agency for Research on Cancer (IARC) working group evaluated benzene in 2009 and noted evidence for a positive association between benzene exposure and NHL risk.
objectiveWe evaluated the association between occupational benzene exposure and NHL among 73,087 women enrolled in the prospective population-based Shanghai Women's Health Study.
methodsBenzene exposure estimates were derived using a previously developed exposure assessment framework that combined ordinal job-exposure matrix intensity ratings with quantitative benzene exposure measurements from an inspection database of Shanghai factories collected between 1954 and 2000. Associations between benzene exposure metrics and NHL (n = 102 cases) were assessed using Cox proportional hazard models, with study follow-up occurring from December 1996 through December 2009.
resultsWomen ever exposed to benzene had a significantly higher risk of NHL [hazard ratio (HR) = 1.87, 95% CI: 1.19, 2.96]. Compared with unexposed women, significant trends in NHL risk were observed for increasing years of benzene exposure (p(trend) = 0.006) and increasing cumulative exposure levels (p(trend) = 0.005), with the highest duration and cumulative exposure tertiles having a significantly higher association with NHL (HR = 2.07, 95% CI: 1.07, 4.01 and HR = 2.16, 95% CI: 1.17, 3.98, respectively).
conclusionsOur findings, using a population-based prospective cohort of women with diverse occupational histories, provide additional evidence that occupational exposure to benzene is associated with NHL risk.
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