Evidence map›Paper›PMID 25748251›Full record

ReviewCurrent opinion in genetics & development2015

Regulation of tissue morphodynamics: an important role for actomyosin contractility.

Michael J Siedlik, Celeste M Nelson

Abstract readReview
In one paragraph

Review in Current opinion in genetics & development, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
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  6. Review
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  12. Computational models of airway branching morphogenesis.Seminars in cell & developmental biology · 2017
    Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. On Buckling Morphogenesis.Journal of biomechanical engineering · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Michael J SiedlikDepartment of Chemical & Biological Engineering, Princeton University, Princeton, NJ 08544, United States.
Celeste M NelsonDepartment of Chemical & Biological Engineering, Princeton University, Princeton, NJ 08544, United States; Department of Molecular Biology, Princeton University, Princeton, NJ 08544, United States. Electronic address: celesten@princeton.edu.

Funding

Mechanical Regulation of Mesenchyme and Mammalian Lung DevelopmentR01HL120142 · NHLBI · PRINCETON UNIVERSITY · PI NELSON, CELESTE M · 2014 to 2017
$1.6M
Spatial patterning of branching morphogenesisR01GM083997 · NIGMS · PRINCETON UNIVERSITY · PI NELSON, CELESTE M · 2008 to 2012
$1.4M
Mechanical regulation of branching morphogenesisR21HL110335 · NHLBI · PRINCETON UNIVERSITY · PI NELSON, CELESTE M · 2011 to 2012
$443k
Exogenous Fluid Forces and Branching of the Mammalian LungR21HL118532 · NHLBI · PRINCETON UNIVERSITY · PI NELSON, CELESTE M · 2014 to 2015
$442k
NHLBI NIH HHS HL110335NHLBI NIH HHS HL118532NHLBI NIH HHS HL120142NHLBI NIH HHS R01 HL120142NHLBI NIH HHS R21 HL110335NHLBI NIH HHS R21 HL118532NIGMS NIH HHS GM083997NIGMS NIH HHS R01 GM083997
6 · The paper itself

Abstract

Forces arising from contractile actomyosin filaments help shape tissue form during morphogenesis. Developmental events that result from actomyosin contractility include tissue elongation, bending, budding, and collective migration. Here, we highlight recent insights into these morphogenetic processes from the perspective of actomyosin contractility as a key regulator. Emphasis is placed on a range of results obtained through live imaging, culture, and computational methods. Combining these approaches in the future has the potential to generate a robust, quantitative understanding of tissue morphodynamics.

Indexed as

ActomyosinBiomechanical PhenomenaCell MovementComputational BiologyDevelopmental BiologyDiagnostic ImagingMorphogenesisActomyosin

Identifiers

PMID25748251
PMCPMC4470836

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.